Additive manufacturing of photo-crosslinked gelatin scaffolds for adipose tissue engineering

L Tytgat, L Van Damme, J Van Hoorick, H Declercq… - Acta Biomaterialia, 2019 - Elsevier
There exists a clear clinical need for adipose tissue reconstruction strategies to repair soft
tissue defects which outperform the currently available approaches. In this respect, additive …

Toward adipose tissue engineering using thiol-norbornene photo-crosslinkable gelatin hydrogels

L Van Damme, J Van Hoorick, P Blondeel… - …, 2021 - ACS Publications
Nowadays, breast implants, lipofilling, and microsurgical free tissue transfer are the most
often applied procedures to repair soft tissue defects resulting from mastectomies …

Extrusion-based 3D printing of photo-crosslinkable gelatin and κ-carrageenan hydrogel blends for adipose tissue regeneration

L Tytgat, L Van Damme, MPO Arevalo… - International journal of …, 2019 - Elsevier
Current soft tissue repair techniques for women with breast cancer remain associated with
several drawbacks including surgical complications and a high resorption rate for lipofilling …

Three-dimensional printing of chemically crosslinked gelatin hydrogels for adipose tissue engineering

NC Negrini, N Celikkin, P Tarsini, S Farè… - …, 2020 - iopscience.iop.org
Despite their outstanding potential and the success that has already been achieved with
three-dimensional (3D) printed hydrogel scaffolds, there has been little investigation into …

Synergistic effect of κ-carrageenan and gelatin blends towards adipose tissue engineering

L Tytgat, M Vagenende, H Declercq, JC Martins… - Carbohydrate …, 2018 - Elsevier
The current paper focuses on the functionalization of κ-carrageenan and gelatin as
extracellular matrix polysaccharide and protein mimic respectively to produce hydrogel films …

Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering

B Huber, K Borchers, GEM Tovar… - Journal of biomaterials …, 2016 - journals.sagepub.com
In vitro engineering of autologous fatty tissue constructs is still a major challenge for the
treatment of congenital deformities, tumor resections or high-graded burns. In this study, we …

Laser fabrication of 3D gelatin scaffolds for the generation of bioartificial tissues

A Ovsianikov, A Deiwick, S Van Vlierberghe, M Pflaum… - Materials, 2011 - mdpi.com
In the present work, the two-photon polymerization (2PP) technique was applied to develop
precisely defined biodegradable 3D tissue engineering scaffolds. The scaffolds were …

Gelatin-methacryloyl (GelMA) hydrogels with defined degree of functionalization as a versatile toolkit for 3D cell culture and extrusion bioprinting

I Pepelanova, K Kruppa, T Scheper, A Lavrentieva - Bioengineering, 2018 - mdpi.com
Gelatin-methacryloyl (GelMA) is a semi-synthetic hydrogel which consists of gelatin
derivatized with methacrylamide and methacrylate groups. These hydrogels provide cells …

Tissue-mimicking gelatin scaffolds by alginate sacrificial templates for adipose tissue engineering

NC Negrini, M Bonnetier, G Giatsidis, DP Orgill, S Farè… - Acta Biomaterialia, 2019 - Elsevier
When adipose tissue (AT) is impaired by trauma or disease, AT engineering could provide a
shelf-ready structural and functional restoration as alternative to current clinical treatments …

Indirect additive manufacturing as an elegant tool for the production of self-supporting low density gelatin scaffolds

J Van Hoorick, H Declercq, A De Muynck… - Journal of Materials …, 2015 - Springer
The present work describes for the first time the production of self-supporting low gelatin
density (< 10 w/v%) porous scaffolds using methacrylamide-modified gelatin as an …