Autocatalysis has been proposed to play critical roles during abiogenesis. These proposals
are at odds with a limited number of known examples of abiotic (and, in particular, inorganic) …

How did chemicals first become organized into systems capable of self-propagation and
adaptive evolution? One possibility is that the first evolvers were chemical ecosystems …

Understanding the emergence of life from (primitive) abiotic components has arguably been
one of the deepest and yet one of the most elusive scientific questions. Notwithstanding the …

Modern cells embody metabolic networks containing thousands of elements and form
autocatalytic sets of molecules that produce copies of themselves. How the first self …

Living organisms are the most complex chemical system known to exist, yet they exploit only
a small constellation of universally conserved metabolites to support indefinite evolution …

The search for chemical processes that might lead to selforganization under potentially
prebiotic conditions has not yet yielded a compelling set of experimental clues for how life …

The construction of hypothetical environments to produce organic molecules such as
metabolic intermediates or amino acids is the subject of ongoing research into the …

How could complex, enzyme-or ribozyme-like molecules first have arisen on planet Earth?
Several authors have suggested autocatalytic cycles as a partial answer to this question …

The importance of autocatalysis spans from practical applications such as in chemically
amplified photoresists, to autocatalysis playing a fundamental role in evolution as well as a …

Most experimental work on the origin of life has focused on either characterizing the
chemical synthesis of particular biochemicals and their precursors or on designing simple …