Improving neurodevelopmental outcome for preterm infants is an important challenge for
neonatal medicine. The disruption of normal brain growth and neurological development is …

Advances in neonatology have led to unprecedented improvements in neonatal survival
such that those born as early as 22 weeks of gestation now have some chance of survival …

The preterm brain is vulnerable to injury through multiple mechanisms, from direct cerebral
injury through ischemia and hemorrhage, indirect injury through inflammatory processes …

Although the prevalence of brain injury and related neurodevelopmental disabilities
resulting from preterm birth are major public health concerns, there are no definite …

Advances in neonatal–perinatal medicine have resulted in increased survival at lower
gestations. Although the incidence of germinal matrix haemorrhage-intraventricular …

Although the mortality rate for preterm infants and the gestational age-specific mortality rate
have dramatically improved over the last 3 to 4 decades, infants born preterm remain …

In recent decades, advances in maternal-fetal, obstetrics, and neonatal medicine have led to
the increased survival of preterm infants. Very preterm infants (< 32 weeks gestation), who …

Infants born at≤ 32+ 6 weeks gestation are at higher risk for intracranial ischemic and
hemorrhagic injuries, which often occur in the first 72 hours postbirth. Antenatal strategies to …

Causes of early brain injury include stroke, birth trauma, metabolic or genetic disorders,
status epilepticus, and asphyxial events. Perinatal asphyxia presents as encephalopathy, or …

A 2007 report from the Institute of Medicine emphasizes preterm birth as an increasingly
common complex condition with multiple risk factors resulting from multiple gene …