Simple Summary Perineural invasion (PNI) as the fourth way for solid tumor metastasis and
invasion has attracted a lot of attention, and axon growth and possible nerve “invasion” to …

Perineural invasion (PNI) can be found in a variety of malignant tumors. It is a sign of tumor
metastasis and invasion and portends the poor prognosis of patients. The pathological …

Perineural invasion (PNI) is defined as the dissemination of neoplastic cells within the
perineural space. PNI can be a strong indicator of malignancy and is linked to poor …

Perineural invasion (PNI) is the process of neoplastic invasion of peripheral nerves and is
considered to be the fifth mode of cancer metastasis. PNI has been detected in head and …

Background Perinueral invasion (PNI) is recognized as an independent adverse prognostic
factor associated with shorter disease free and disease specific survival in a range of …

Purpose Perineural invasion (PNI) is the neoplastic invasion of nerves by cancer cells, a
process that may prove to be another metastatic route besides direct invasion, lymphatic …

Perineural invasion (PNI) is characterized by an encounter between the cancer cells and
neuronal fibers and holds an extremely poor prognosis for malignant tumors. The exact …

Perineural invasion (PNI) refers to the cancerous invasion of nerves. It provides an
alternative route for metastatic invasion and can exist independently in the absence of …

The invasion of nerves by cancer cells, or perineural invasion (PNI), is potentiated by the
nerve microenvironment and is associated with adverse clinical outcomes. However, the …

Neural invasion (NI) is the invasion of cancer cells into nerves, influencing the pathological
characteristics of malignant tumors. NI promotes metastasis and is associated with reduced …