Intrinsically disordered proteins (IDPs) are prevalent in eukaryotes, performing signaling and
regulatory functions. Often associated with human diseases, they constitute drug …

Intrinsically disordered proteins (IDPs) are emerging as attractive drug targets by virtue of
their physiological ubiquity and their prevalence in various diseases, including cancer …

Intrinsically disordered proteins (IDPs) are emerging as attractive drug targets by virtue of
their prevalence in various diseases including cancer. Drug development targeting IDPs is …

Cancer cells activate stress-response mechanisms to adapt themselves to a variety of
stressful conditions. Among these protective mechanisms, those controlled by the stress …

Intrinsically disordered proteins (IDPs) do not have a well-defined structure under
physiological conditions, but they have key roles in cell signaling and regulation, and they …

Protein–protein interactions involving disordered partners have unique features and
represent prominent targets in drug discovery processes. Intrinsically Disordered Proteins …

Introduction: There is a natural abundance of intrinsically disordered proteins or intrinsically
disordered protein regions (IDPs or IDPRs), that is, biologically active proteins/regions …

Intrinsically disordered proteins (IDPs) were found to be widely associated with human
diseases and may serve as potential drug design targets. However, drug design targeting …

Introduction: Intrinsically disordered proteins (IDPs) and intrinsically disordered protein
regions (IDPRs) have gained wide recognition over the past decade due to their versatile …

Intrinsically disordered proteins (IDPs) are prevalent in eukaryotes; in humans, they are
often associated with diseases. The protein NUPR1 is a multifunctional IDP involved in the …