Management of chronic obstructive pulmonary disease beyond the lungs

LEGW Vanfleteren, MA Spruit, EFM Wouters… - The Lancet …, 2016 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is an umbrella term that covers many
clinical subtypes with clearly different pulmonary and extra-pulmonary characteristics, but …

Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management

PG Woodruff, A Agusti, N Roche, D Singh, FJ Martinez - The Lancet, 2015 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a common, complex, and heterogeneous
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …

Controversies in treatment of chronic obstructive pulmonary disease

KF Rabe, JA Wedzicha - The Lancet, 2011 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a chronic disorder with substantial
comorbidity and major effects attributable to the high morbidity and mortality rates. Despite …

[HTML][HTML] COPD exacerbations: defining their cause and prevention

JA Wedzicha, TAR Seemungal - The lancet, 2007 - thelancet.com
Exacerbations of chronic obstructive pulmonary disease (COPD) are episodes of worsening
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …

Management of severe COPD

EFM Wouters - The Lancet, 2004 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide, and the burden of the disorder will continue to increase over the next 20 years …

The burden of chronic obstructive pulmonary disease

P Vermeire - Respiratory medicine, 2002 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a disease state characterized by chronic
airflow limitation that is not fully reversible, with a precise definition varying between different …

Update on the management of COPD

BR Celli - Chest, 2008 - Elsevier
COPD is highly prevalent and will continue to be an increasing cause of morbidity and
mortality worldwide. COPD is now viewed under a new paradigm as preventable and …

COPD‐X Australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update

IA Yang, JL Brown, J George, S Jenkins… - Medical Journal of …, 2017 - Wiley Online Library
Introduction: Chronic obstructive pulmonary disease (COPD) is characterised by persistent
respiratory symptoms and chronic airflow limitation, and is associated with exacerbations …

Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

D Stolz, T Mkorombindo, DM Schumann, A Agusti… - The Lancet, 2022 - thelancet.com
Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

The future of chronic obstructive pulmonary disease treatment—difficulties of and barriers to drug development

FJ Martinez, JF Donohue, SI Rennard - The Lancet, 2011 - thelancet.com
Although chronic obstructive pulmonary disease (COPD) is a major global health problem
with a rising incidence and morbidity, few pharmacotherapeutic advances have been made …