Abstract c‐Jun N‐terminal kinase (JNK) is involved in cancer cell apoptosis; however,
emerging evidence indicates that this Janus signaling promotes cancer cell survival. JNK …

The JNKs are master protein kinases that regulate many physiological processes, including
inflammatory responses, morphogenesis, cell proliferation, differentiation, survival and …

Abstract c-Jun N-terminal kinase (JNK) signalling regulates both cancer cell apoptosis and
survival. Emerging evidence show that JNK promoted tumour progression is involved in …

Jun N-terminal kinases or JNKs have been shown to be involved in a wide array of signaling
events underlying tumorigenesis and tumor progression. Through its interaction with a …

Overwhelming) are a set of key stress-responsive kinases that mediate cell apoptosis, which
is an important process for tumor suppression. However, JNKs have also been implicated in …

JNKs (c-Jun N-terminal kinases) belong to mitogen-activated protein kinases' family and
become activated by several growth factors, stress, radiation, and other extracellular signals …

ABSTRACT JNK is a key regulator of many cellular events, including programmed cell death
(apoptosis). In the absence of NF-κB activation, prolonged JNK activation contributes to TNF …

The c-Jun-NH 2-terminal kinase (JNK) signaling pathway plays a critical role in regulating
cell fate, being implicated in a multitude of diseases ranging from cancer to neurological and …

The literature provides strong precedent for both protumorigenic and tumor suppressor roles
for the c-Jun N-terminal kinases (JNKs) in the setting of oncogenesis. Clearly, JNKs are …

The c-Jun N-terminal kinase (JNK) group of mitogen-activated protein kinases (MAPKs) is
activated in mammalian cells by environmental stress, pro-inflammatory cytokines, and …