[PDF][PDF] CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity
To better understand primary and recall T cell responses during coronavirus disease 2019
(COVID-19), it is important to examine unmanipulated severe acute respiratory syndrome …
(COVID-19), it is important to examine unmanipulated severe acute respiratory syndrome …
[PDF][PDF] CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses
Efforts are being made worldwide to understand the immune response to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus …
respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus …
[HTML][HTML] SARS-CoV-2–specific CD8+ T cell responses in convalescent COVID-19 individuals
Characterization of the T cell response in individuals who recover from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical to understanding its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical to understanding its …
SARS-CoV-2 epitope–specific CD4+ memory T cell responses across COVID-19 disease severity and antibody durability
RW Nelson, Y Chen, OL Venezia, RM Majerus… - Science …, 2022 - science.org
CD4+ T cells are central to long-term immunity against viruses through the functions of T
helper 1 (TH1) and T follicular helper (TFH) cell subsets. To better understand the role of …
helper 1 (TH1) and T follicular helper (TFH) cell subsets. To better understand the role of …
[PDF][PDF] SARS-CoV-2 epitopes are recognized by a public and diverse repertoire of human T cell receptors
Understanding the hallmarks of the immune response to SARS-CoV-2 is critical for fighting
the COVID-19 pandemic. We assessed antibody and T cell reactivity in convalescent COVID …
the COVID-19 pandemic. We assessed antibody and T cell reactivity in convalescent COVID …
[HTML][HTML] Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals
S Mahajan, V Kode, K Bhojak, C Karunakaran, K Lee… - Scientific reports, 2021 - nature.com
The COVID-19 pandemic has revealed a range of disease phenotypes in infected patients
with asymptomatic, mild, or severe clinical outcomes, but the mechanisms that determine …
with asymptomatic, mild, or severe clinical outcomes, but the mechanisms that determine …
[PDF][PDF] Unbiased screens show CD8+ T cells of COVID-19 patients recognize shared epitopes in SARS-CoV-2 that largely reside outside the spike protein
AP Ferretti, T Kula, Y Wang, DMV Nguyen… - Immunity, 2020 - cell.com
Developing effective strategies to prevent or treat coronavirus disease 2019 (COVID-19)
requires understanding the natural immune response to severe acute respiratory syndrome …
requires understanding the natural immune response to severe acute respiratory syndrome …
Identification of SARS-CoV-2 nucleocapsid and spike T-cell epitopes for assessing T-cell immunity
Developing optimal T-cell response assays to severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2) is critical for measuring the duration of immunity to this …
coronavirus type 2 (SARS-CoV-2) is critical for measuring the duration of immunity to this …
[HTML][HTML] Immunogenic T cell epitopes of SARS-CoV-2 are recognized by circulating memory and naïve CD8 T cells of unexposed individuals
I Quiros-Fernandez, M Poorebrahim, E Fakhr… - …, 2021 - thelancet.com
Background Recent studies have provided evidence of T cell reactivity to Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in significant numbers of non-infected …
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in significant numbers of non-infected …
[PDF][PDF] Profiling CD8+ T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants
Cellular immunity is important in determining the disease severity of COVID-19 patients.
However, current understanding of SARS-CoV-2 epitopes mediating cellular immunity is …
However, current understanding of SARS-CoV-2 epitopes mediating cellular immunity is …
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