The influence of Toll‑like receptor (TLR) 4/myeloid differentiation factor (MyD) 88 signaling
on the invasion and metastasis of cancer cells has been previously reported. The purpose of …

Objective: To investigate the expression of TLR4/MyD88 in breast cancer, and explore the
relationship between their expression and breast cancer tumor growth and invasion …

Toll-like receptor (TLR) 4-mediated signaling has been implicated in tumor cell invasion,
survival, and metastasis in a variety of cancers. This study investigated the expression and …

Background Tumor cell expression of Toll-like receptors (TLRs) can promote inflammation
and cell survival in the tumor microenvironment. Toll-like receptor 4 (TLR4) signaling in …

Triggering of Toll-like receptor 4 (TLR4) on tumor cells has been found to promote tumor
progression by promoting tumor cell proliferation and survival. So far, however, the effect of …

Purpose Breast cancer remains a major cause of death in women worldwide, and tumor
metastasis is the leading cause of death in breast cancer patients after conventional …

MDA-MB-231 breast cancer cells have a high invasive potential, yet the mechanisms
involved are not known. This study showed that Toll-like receptor 2 (TLR2) was highly …

Abstract Toll-like receptor 9 (TLR9) is a cellular DNA-receptor, which is widely expressed in
cancer. Synthetic TLR9-ligands induce cancer cell invasion in vitro, but the role of TLR9 in …

Abstract Background Toll-like receptors (TLRs) have garnered an extraordinary amount of
interest in cancer research due to their role in tumor progression. By activating the …

Toll‐like receptor 9 (TLR9) activates the innate immune response when exposed to non‐
methylated CpG‐DNA. TLR9 was recently shown to be expressed by cancer cells which …