As platelets aggregate and activate at the site of vascular injury to stem bleeding, they are
subjected to a myriad of biochemical and biophysical signals and cues. As clot formation …

Platelet aggregation at the site of vascular injury is essential in clotting. During this process,
platelets are bridged by soluble fibrinogen that binds surface integrin receptors. One mystery …

Haemostasis occurs at sites of vascular injury, where flowing blood forms a clot, a dynamic
and heterogeneous fibrin-based biomaterial. Paramount in the clot's capability to stem …

During clot formation, platelets are subjected to various different signals and cues as they
dynamically interact with extracellular matrix proteins such as von Willebrand factor (vWF) …

Blood clot contraction plays an important role in prevention of bleeding and in thrombotic
disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the …

The vasculature is a dynamic environment in which blood platelets constantly survey the
endothelium for sites of vessel damage. The formation of a mechanically coherent …

Platelets contract forcefully after their activation, contributing to the strength and stability of
platelet aggregates and fibrin clots during blood coagulation. Viscoelastic approaches can …

Platelets interact with fibrin polymers to form blood clots at sites of vascular injury,,. Bulk
studies have shown clots to be active materials, with platelet contraction driving the …

Platelets interact with multiple adhesion proteins during thrombogenesis, yet little is known
about their ability to assemble fibronectin matrix. In vitro three-dimensional superresolution …

Platelets play an important role in hemostasis by forming a thrombotic plug that seals the
vessel wall and promotes vascular healing. After platelets adhere and aggregate at the …