The functional and clinical roles of liquid biopsy in patient-derived models

Z Zhu, E Hu, H Shen, J Tan, S Zeng - Journal of Hematology & Oncology, 2023 - Springer
The liquid biopsy includes the detection of circulating tumor cells (CTCs) and CTC clusters
in blood, as well as the detection of, cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) …

Combinatorial power of cfDNA, CTCs and EVs in oncology

C Keup, R Kimmig, S Kasimir-Bauer - Diagnostics, 2022 - mdpi.com
Liquid biopsy is a promising technique for clinical management of oncological patients. The
diversity of analytes circulating in the blood useable for liquid biopsy testing is enormous …

Liquid biopsy: current technology and clinical applications

M Nikanjam, S Kato, R Kurzrock - Journal of hematology & oncology, 2022 - Springer
Liquid biopsies are increasingly used for cancer molecular profiling that enables a precision
oncology approach. Circulating extracellular nucleic acids (cell-free DNA; cfDNA) …

Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB)

C Rolfo, AF Cardona, M Cristofanilli, L Paz-Ares… - Critical Reviews in …, 2020 - Elsevier
Precision medicine was born with the development of new diagnostic techniques and
targeted drugs, yielding better outcomes in cancer care. With the evolution and increasing …

Circulating tumor cells in precision oncology: Clinical applications in liquid biopsy and 3D organoid model

C Yang, BR Xia, WL Jin, G Lou - Cancer cell international, 2019 - Springer
Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with
solid tumors, which function as a seed for metastases. Cancer cells metastasize through the …

Looking to the future of early detection in cancer: liquid biopsies, imaging, and artificial intelligence

S Foser, K Maiese, SR Digumarthy… - Clinical …, 2024 - academic.oup.com
Cancer is a highly heterogeneous disease that is frequently diagnosed at an advanced
stage with the presence of metastatic disease resulting in limited treatment options and a …

Cancer diagnosis: from tumor to liquid biopsy and beyond

R Vaidyanathan, RH Soon, P Zhang, K Jiang, CT Lim - Lab on a Chip, 2019 - pubs.rsc.org
Technological advancements in research on circulating biomarkers from patient derived
blood have enabled a less invasive means of diagnosing non-hematologic cancers …

[HTML][HTML] Liquid biopsy in the era of immuno-oncology: is it ready for prime-time use for cancer patients?

P Hofman, S Heeke, C Alix-Panabières, K Pantel - Annals of Oncology, 2019 - Elsevier
The emergence of immunotherapy in oncology requires the discovery, validation and
subsequent adoption of robust, sensitive and specific predictive and prognostic biomarkers …

Clinical implementation and current advancement of blood liquid biopsy in cancer

K Watanabe, Y Nakamura, SK Low - Journal of Human Genetics, 2021 - nature.com
Liquid biopsies have been receiving tremendous attentions as easy, rapid, and non-invasive
tools for cancer diagnosis. Liquid biopsy can be performed repeatedly for disease …

[HTML][HTML] Liquid biopsy in the clinical management of cancers

HY Ho, KS Chung, CM Kan, SC Wong - International Journal of Molecular …, 2024 - mdpi.com
Liquid biopsy, a noninvasive diagnosis that examines circulating tumor components in body
fluids, is increasingly used in cancer management. An overview of relevant literature …