[PDF][PDF] Selective and sensitive method for the determination of metoprolol in human plasma using liquid chromatography coupled with tandem mass spectrometry

P Venkateswarlu, B Kumar, K Seshaiah… - Acta Pharmaceutica, 2010 - sciendo.com
A high-performance liquid chromatography-tandem mass spectrometric method was
developed and validated for the determination of metoprolol in human plasma. The analyte …

Liquid chromatography tandem mass spectrometry method for simultaneous determination of metoprolol tartrate and ramipril in human plasma

KV Gowda, U Mandal, PS Selvan… - … of Chromatography B, 2007 - Elsevier
A simple, rapid, sensitive and specific liquid chromatography-tandem mass spectrometry
method was developed and validated for quantification of metoprolol tartrate (MT) and …

[PDF][PDF] A validated HPLC method for estimation of metoprolol in human plasma

M Aqil, A Ali, A Ahad, Y Sultana, AK Najmi… - Acta …, 2007 - Citeseer
SUMMARY A high-performance reversed-phase liquid chromatographic method for
quantification of metoprolol tartrate (MT) in human plasma is presented. AC 18 column was …

Efficient high-performance liquid chromatographic assay for the simultaneous determination of metoprolol and two main metabolites in human urine by solid-phase …

FCK Chiu, LA Damani, RC Li, B Tomlinson - Journal of Chromatography B …, 1997 - Elsevier
An improved, more efficient method for the determination of metoprolol and its two
metabolites in human urine is reported. The simultaneous analysis of the zwitterionic …

Determination of metoprolol and its two metabolites in human plasma and urine by high performance liquid chromatography with fluorescence detection and its …

T Xu, S Bao, P Geng, J Luo, L Yu, P Pan, Y Chen… - … of Chromatography B, 2013 - Elsevier
A simple, specific and sensitive HPLC method has been developed for the determination of
metoprolol and its two metabolites in human plasma and urine. Separation of metoprolol, α …

[PDF][PDF] Estimation of metoprolol in human plasma by HPLC method

I Mahvash, RH Shobha Rani - Int J Pharm Pharm Sci, 2014 - academia.edu
Objective: The current project was undertaken to develop and validate a simple method for
estimation of metoprolol in human plasma using HPLC. Before implementing the method on …

Development and validation of a stereoselective liquid chromatography–tandem mass spectrometry assay for quantification of S-and R-metoprolol in human plasma

BP Jensen, CF Sharp, SJ Gardiner, EJ Begg - Journal of Chromatography B, 2008 - Elsevier
A stereoselective liquid chromatography–tandem mass spectrometry assay was developed
and validated for quantification of S-and R-metoprolol at concentrations of 0.5–50μg/L in …

Development and validation of GC-MS method for determination of metoprolol in human urine

B Yilmaz, S Arslan - Journal of chromatographic science, 2010 - academic.oup.com
This paper describes a specific, sensitive, and accurate gas chromatography-mass
spectrometry method for determination of metoprolol in human urine after derivatization with …

A validated high-resolution accurate mass LC-MS assay for quantitative determination of metoprolol and α-hydroxymetoprolol in human serum for application in …

S Postma-Kunnen, JP Yska, G Hommema… - Journal of Applied …, 2017 - research.rug.nl
To determine metoprolol and its metabolite α-hydroxymetoprolol in human serum we
validated a method on an LC system with an Exactive® Orbitrap mass spectrometer (Thermo …

Determination of metoprolol in human plasma and urine by high‐performance liquid chromatography with fluorescence detection

B Yilmaz, A Asci, S Arslan - Journal of Separation Science, 2010 - Wiley Online Library
A simple, specific and sensitive HPLC method has been developed for the determination of
metoprolol in human plasma and urine. Separation of metoprolol and atenolol (internal …