Biocompatibility assessment of Si-based nano-and micro-particles

H Jaganathan, B Godin - Advanced drug delivery reviews, 2012 - Elsevier
Silicon is one of the most abundant chemical elements found on the Earth. Due to its unique
chemical and physical properties, silicon based materials and their oxides (eg silica) have …

Nanoengineered silica: Properties, applications and toxicity

AM Mebert, CJ Baglole, MF Desimone… - Food and Chemical …, 2017 - Elsevier
Silica nanoparticles are widely used for biomedical purposes, but also in cosmetic products,
food, the car industry, paints, etc. Considering their mega production, one should not ignore …

Effect of surface modification of silica nanoparticles on toxicity and cellular uptake by human peripheral blood lymphocytes in vitro

A Lankoff, M Arabski, A Wegierek-Ciuk… - …, 2013 - Taylor & Francis
Silica nanoparticles have an interesting potential in drug delivery, gene therapy and
molecular imaging due to the possibility of tailoring their surface reactivity that can be …

[HTML][HTML] Silica nanoparticles: Biomedical applications and toxicity

Y Huang, P Li, R Zhao, L Zhao, J Liu, S Peng… - Biomedicine & …, 2022 - Elsevier
Silica nanoparticles (SiNPs) are composed of silicon dioxide, the most abundant compound
on Earth, and are used widely in many applications including the food industry, synthetic …

In vivo toxicologic study of larger silica nanoparticles in mice

WT Chan, CC Liu, JS Chiang Chiau… - International journal …, 2017 - Taylor & Francis
Silica nanoparticles (SiNPs) are being studied and used for medical purposes. As
nanotechnology grows rapidly, its biosafety and toxicity have frequently raised concerns …

In vivo toxicity of orally administrated silicon dioxide nanoparticles in healthy adult mice

R Hassankhani, M Esmaeillou, AA Tehrani… - … Science and Pollution …, 2015 - Springer
The increasing use of silica nanoparticles (SiNPs) in various applications including
industrial, agriculture, and medicine has raised concerns about their potential risks to human …

In Vivo Toxicity of Intravenously Administered Silica and Silicon Nanoparticles

S Ivanov, S Zhuravsky, G Yukina, V Tomson, D Korolev… - Materials, 2012 - mdpi.com
Both silicon and silica nanoparticles (SiNPs and SiO2NPs, respectively) are currently
considered to be promising carriers for targeted drug delivery. However, the available data …

Prospects and hazards of silica nanoparticles: Biological impacts and implicated mechanisms

R Ding, Y Li, Y Yu, Z Sun, J Duan - Biotechnology Advances, 2023 - Elsevier
With the thrive of nanotechnology, silica nanoparticles (SiNPs) have been extensively
adopted in the agriculture, food, cosmetic, and even biomedical industries. Due to the mass …

The toxicity of silica nanoparticles to the immune system

L Chen, J Liu, Y Zhang, G Zhang, Y Kang, A Chen… - …, 2018 - Taylor & Francis
Silicon-based materials and their oxides are widely used in drug delivery, dietary
supplements, implants and dental fillers. Silica nanoparticles (SiNPs) interact with …

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

R Mohammadpour, DL Cheney, JW Grunberger… - Journal of Controlled …, 2020 - Elsevier
Chronic toxicity evaluations of nanotechnology-based drugs are essential to support
initiation of clinical trials. Ideally such evaluations should address the dosing strategy in …