Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems

TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

Formulation approaches in enhancement of patient compliance to oral drug therapy

A Shahiwala - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: Disease management of outdoor patients is mainly affected by patient
compliance to the drug therapy, which in turn is governed by patient convenience. Failure to …

A systematic overview of systematic reviews evaluating medication adherence interventions

LJ Anderson, TK Nuckols, C Coles… - American Journal of …, 2020 - academic.oup.com
Purpose To systematically summarize evidence from multiple systematic reviews (SRs)
examining interventions addressing medication nonadherence and to discern differences in …

Drug delivery approaches in addressing clinical pharmacology-related issues: opportunities and challenges

H Wen, H Jung, X Li - The AAPS journal, 2015 - Springer
Various drug delivery approaches can be used to maximize therapeutic efficacy and
minimize side effects, by impacting absorption, distribution, metabolism, and elimination …

[HTML][HTML] Is there a threshold for medication adherence? Lessons learnt from electronic monitoring of drug adherence

M Burnier - Frontiers in pharmacology, 2019 - frontiersin.org
Medication adherence is a well-recognized problem in the management of patients with
chronic diseases needing a long-term pharmacotherapy. While fighting against non …

[HTML][HTML] Medication adherence: The elephant in the room

J Kim, K Combs, J Downs, F Tillman - Us Pharm, 2018 - uspharmacist.com
Medication adherence can have a more direct impact on patient outcomes than the specific
treatment itself; it is estimated that adherence to chronic medications is about 50 …

Using theory to explore the determinants of medication adherence; moving away from a one-size-fits-all approach

C Easthall, N Barnett - Pharmacy, 2017 - mdpi.com
Non-adherence to prescribed medicines has been described as “a worldwide problem of
striking magnitude”, diminishing treatment effects and wasting resources. Evidence …

Supporting adherence to medicines for long-term conditions

R Horne, V Cooper, V Wileman… - European …, 2019 - econtent.hogrefe.com
Pharmaceutical prescriptions are core to the treatment of most chronic illnesses, yet only half
are taken as prescribed. Despite the high costs of nonadherence to individuals and society …

Drug delivery of the future: Chasing the invisible gorilla

K Park - Journal of Controlled Release, 2016 - Elsevier
For more than 60 years drug delivery systems have produced numerous controlled release
formulations helping patients improve compliance and maximize the drug efficacy …

Poor medication adherence in type 2 diabetes: recognizing the scope of the problem and its key contributors

WH Polonsky, RR Henry - Patient preference and adherence, 2016 - Taylor & Francis
At least 45% of patients with type 2 diabetes (T2D) fail to achieve adequate glycemic control
(HbA1c< 7%). One of the major contributing factors is poor medication adherence. Poor …