Behavioral profiles of mouse models for autism spectrum disorders

E Ey, CS Leblond, T Bourgeron - Autism research, 2011 - Wiley Online Library
Autism spectrum disorders (ASD) are characterized by impairments in reciprocal social
communication, and stereotyped verbal and nonverbal behaviors. In approximately 10–25 …

Overview of mouse models of autism spectrum disorders

AL Bey, Y Jiang - Current protocols in pharmacology, 2014 - Wiley Online Library
This overview describes many well characterized mouse models of autism spectrum
disorders (ASDs). Mouse models considered here were selected because they are …

Autism spectrum disorders: translating human deficits into mouse behavior

E Pasciuto, SC Borrie, AK Kanellopoulos… - Neurobiology of learning …, 2015 - Elsevier
Abstract Autism Spectrum Disorders are a heterogeneous group of neurodevelopmental
disorders, with rising incidence but little effective therapeutic intervention available …

Monogenic mouse models of autism spectrum disorders: common mechanisms and missing links

SW Hulbert, YH Jiang - Neuroscience, 2016 - Elsevier
Autism spectrum disorders (ASDs) present unique challenges in the fields of genetics and
neurobiology because of the clinical and molecular heterogeneity underlying these …

Mouse models of autism spectrum disorders: the challenge for behavioral genetics

SS Moy, JJ Nadler, TR Magnuson… - American Journal of …, 2006 - Wiley Online Library
Autism is a severe neurodevelopmental disorder, which typically emerges early in
childhood. The core symptoms of autism include deficits in social interaction, impaired …

Modeling autism-relevant behavioral phenotypes in rats and mice: Do 'autistic'rodents exist?

M Servadio, LJMJ Vanderschuren… - Behavioural …, 2015 - journals.lww.com
Autism spectrum disorders (ASD) are among the most severe developmental psychiatric
disorders known today, characterized by impairments in communication and social …

Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future

JL Silverman, A Thurm, SB Ethridge… - Genes, brain and …, 2022 - Wiley Online Library
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …

Genetic animal models for autism spectrum disorder

JC Schroeder, D Reim, TM Boeckers… - Social behavior from …, 2017 - Springer
Autism spectrum disorder (ASD) affects approximately 1% of the human population and has
a strong genetic component. Hence, the recent discovery of major “ASD genes” has …

[HTML][HTML] Clinical and neurobiological relevance of current animal models of autism spectrum disorders

KC Kim, EL Gonzales, MT Lázaro, CS Choi… - Biomolecules & …, 2016 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
and communication impairments, as well as repetitive and restrictive behaviors. The …

Multiple autism-like behaviors in a novel transgenic mouse model

SM Hamilton, CM Spencer, WR Harrison… - Behavioural brain …, 2011 - Elsevier
Autism spectrum disorder (ASD) diagnoses are behaviorally based with no defined
universal biomarkers, occur at a 1: 110 ratio in the population, and predominantly affect …