The molecular basis of CaMKII function in synaptic and behavioural memory
J Lisman, H Schulman, H Cline - Nature Reviews Neuroscience, 2002 - nature.com
Long-term potentiation (LTP) in the CA1 region of the hippocampus has been the primary
model by which to study the cellular and molecular basis of memory. Calcium/calmodulin …
model by which to study the cellular and molecular basis of memory. Calcium/calmodulin …
A working model of CaM kinase II activity in hippocampal long-term potentiation and memory
K Fukunaga, E Miyamoto - Neuroscience research, 2000 - Elsevier
Recent advances in molecular genetics provide strong evidence for a relationship between
hippocampal long-term potentiation (LTP) and hippocampus-dependent memory. The α …
hippocampal long-term potentiation (LTP) and hippocampus-dependent memory. The α …
Synaptic memory survives molecular turnover
J Lee, X Chen, RA Nicoll - Proceedings of the National …, 2022 - National Acad Sciences
Activation of Ca2+/calmodulin-dependent kinase II (CaMKII) plays a critical role in long-term
potentiation (LTP), a long accepted cellular model for learning and memory. However, how …
potentiation (LTP), a long accepted cellular model for learning and memory. However, how …
Synaptic memory and CaMKII
RA Nicoll, H Schulman - Physiological reviews, 2023 - journals.physiology.org
Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …
were discovered within a decade of each other and have been inextricably intertwined ever …
[HTML][HTML] Memory erasure experiments indicate a critical role of CaMKII in memory storage
T Rossetti, S Banerjee, C Kim, M Leubner, C Lamar… - Neuron, 2017 - cell.com
The abundant synaptic protein CaMKII is necessary for long-term potentiation (LTP) and
memory. However, whether CaMKII is required only during initial processes or whether it …
memory. However, whether CaMKII is required only during initial processes or whether it …
Synaptic memory requires CaMKII
Long-term potentiation (LTP) is arguably the most compelling cellular model for learning and
memory. While the mechanisms underlying the induction of LTP ('learning') are well …
memory. While the mechanisms underlying the induction of LTP ('learning') are well …
Novel insights into CaMKII function and regulation during memory formation
Ca2+/calmodulin-dependent kinase II (CaMKII) is an abundant synaptic signalling molecule
that is essential for memory formation and the induction of synaptic potentiation. Additionally …
that is essential for memory formation and the induction of synaptic potentiation. Additionally …
Reversal of synaptic memory by Ca2+/calmodulin-dependent protein kinase II inhibitor
M Sanhueza, CC McIntyre, JE Lisman - Journal of Neuroscience, 2007 - Soc Neuroscience
Long-term potentiation (LTP) is an activity-dependent strengthening of synapses that is
thought to underlie memory storage. Ca2+/calmodulin-dependent protein kinase II (CaMKII) …
thought to underlie memory storage. Ca2+/calmodulin-dependent protein kinase II (CaMKII) …
[HTML][HTML] CaMKII isoforms in learning and memory: localization and function
G Zalcman, N Federman, A Romano - Frontiers in molecular …, 2018 - frontiersin.org
Calcium/calmodulin-dependent protein kinase II (CaMKII) is a key protein kinase in neural
plasticity and memory, as have been shown in several studies since the first evidence in …
plasticity and memory, as have been shown in several studies since the first evidence in …
CaM kinase II in long-term potentiation
K Fukunaga, D Muller, E Miyamoto - Neurochemistry international, 1996 - Elsevier
The observation that autophosphorylation converts CaM kinase II from the Ca2+-dependent
form to the Ca2+-independent form has led to speculation that the formation of the Ca2+ …
form to the Ca2+-independent form has led to speculation that the formation of the Ca2+ …