Intravenous tissue plasminogen activator for patients with minor ischemic stroke

BN Huisa, R Raman, W Neil, K Ernstrom… - Journal of Stroke and …, 2012 - Elsevier
BACKGROUND: Patients with minor ischemic stroke (MIS) are frequently excluded from
thrombolytic therapy. Denial of therapy to these patients, however, remains controversial …

Intravenously administered tissue plasminogen activator useful in milder strokes? A meta-analysis

LLL Yeo, R Ho, P Paliwal, R Rathakrishnan… - Journal of Stroke and …, 2014 - Elsevier
Background The dilemma of whether to treat mild strokes with tPA is a chronic problem. We
performed a meta-analysis and metaregression of the published literature to determine the …

Utility of computed tomographic perfusion in thrombolysis for minor stroke

FC Ng, S Coote, T Frost, C Bladin, PM Choi - Stroke, 2016 - Am Heart Assoc
Background and Purpose—The use of thrombolysis in acute minor ischemic stroke (MIS)
remains controversial. We sought to determine the safety and efficacy of intravenous tissue …

Intravenous thrombolysis or medical management for minor strokes

WJ Tu, Y Xu, Y Liu, J Li, J Du… - Thrombosis and …, 2023 - thieme-connect.com
Objective To evaluate the outcomes of acute ischemic stroke patients with minor deficits
treated with either intravenous thrombolysis (IVT) or routine medical management (MM) …

Thrombolysis for acute minor stroke: outcome and barriers to management: results from the RESUVAL Stroke Network

C Laurencin, F Philippeau, K Blanc-Lasserre… - Cerebrovascular …, 2015 - karger.com
Background: We evaluated the management, outcome and haemorrhagic risk in a cohort of
ischaemic stroke patients with mild symptoms treated with intravenous tissue plasminogen …

Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience

… Institute of Neurological Disorders Stroke rt-PA … - Annals of emergency …, 2005 - Elsevier
STUDY OBJECTIVE: Acute ischemic stroke patients eligible for tissue plasminogen activator
and with less severe neurologic deficits, although still generally benefiting from therapy, may …

Efficacy and safety of intravenous recombinant tissue plasminogen activator in mild ischaemic stroke: a meta-analysis

S You, A Saxena, X Wang, WY Tan, Q Han… - Stroke and vascular …, 2018 - svn.bmj.com
The benefits and safety of intravenous recombinant tissue plasminogen activator (IV-tPA) for
patients with mild ischaemic stroke (MIS) are still unclear. The objective of this meta-analysis …

Does mild deficit for patients with stroke justify the use of intravenous tissue plasminogen activator?

AE Hassan, H Zacharatos, B Hassanzadeh… - Journal of Stroke and …, 2010 - Elsevier
Intravenous (IV) tissue plasminogen activator (t-PA) is an effective medication currently used
to treat acute ischemic stroke within 3 hours of symptom onset in patients with an identifiable …

Effect of rt-PA intravenous thrombolysis on the prognosis of patients with minor ischemic stroke

Y Han, G Li, Y Tang, B Zhang, Y Zhan… - Neurological …, 2021 - Taylor & Francis
Aims The evidence of rt-PA intravenous thrombolysis in patients with minor ischemic stroke
(MIS) is still controversial. This study aims to investigate the effect of rt-PA intravenous …

[PDF][PDF] Obstacles to the use of intravenous tissue plasminogen activator for acute ischemic stroke. Is time the only barrier?

P Laloux, V Thijs, A Peeters… - Acta neurologica belgica, 2007 - academia.edu
Background and aims: The short time window is frequently cited as the main reason for
exclusion of intravenous tissue plasminogen activator (tPA) in acute stroke. Identifying and …