Antigen presenting cells such as myeloid dendritic cells (DCs) are key sentinels of the innate
immune system. In response to pathogen recognition and innate immune stimulation, DCs …

APCs such as myeloid dendritic cells (DCs) are key sentinels of the innate immune system.
In response to pathogen recognition and innate immune stimulation, DCs transition from an …

Highlights•Transcriptional requirements of DC subset development.•Batf3-dependent
CD8α+ DCs mediate type I immune responses.•CD11b+ DCs orchestrate ILC3 and TH 17 …

Dendritic cells (DCs) orchestrate immune responses according to their state of maturation. In
response to infection, DCs differentiate into mature cells that initiate immune responses …

Dendritic cells (DCs) are sentinel immune cells that form a critical bridge linking the innate
and adaptive immune systems. Extensive research addressing the cellular origin and …

Dendritic cells are the major specialized antigen-presenting cells, thereby connecting innate
and adaptive immunity. Because of their role in establishing adaptive immunity, they have …

Transcription factors play a determining role in lineage commitment and cell differentiation.
Interferon regulatory factor 8 (IRF8) is a lineage determining transcription factor in …

The development and cooperation of distinct subsets of antigen-presenting cells, particularly
dendritic cells (DCs), may be critical for maintaining homeostatic immune responses …

Dendritic cells (DCs) are specialized sentinels responsible for coordinating adaptive
immunity. This function is dependent upon coupled sensitivity to environmental signs of …

Dendritic cells (DCs) drive both adaptive and innate immunity. Recent findings support the
notion that distinct subsets of classical DCs favor alternative modules of immunity, acting on …