Zingerone attenuates vancomycin-induced hepatotoxicity in rats through regulation of oxidative stress, inflammation and apoptosis

S Kucukler, E Darendelioğlu, C Caglayan, A Ayna… - Life Sciences, 2020 - Elsevier
Aim Vancomycin (VCM) is a glycopeptide antibiotic widely used to treat serious infections
caused by methicillin-resistant Staphylococcus aureus and has been associated with some …

Citronellal ameliorates doxorubicin‐induced hepatotoxicity via antioxidative stress, antiapoptosis, and proangiogenesis in rats

X Liu, Y Qiu, Y Liu, N Huang, C Hua… - … of biochemical and …, 2021 - Wiley Online Library
Doxorubicin (DOX) is a very effective broad‐spectrum anticancer drug, yet its clinical
application is badly restricted due to its serious side effects. Citronellal (CT), a specialized …

[HTML][HTML] Therapeutic efficacy of zingerone against vancomycin-induced oxidative stress, inflammation, apoptosis and aquaporin 1 permeability in rat kidney

FM Kandemir, S Yildirim, S Kucukler… - Biomedicine & …, 2018 - Elsevier
Vancomycin (VCM) is a glycopeptidic broad-spectrum antibiotic against methicillin-resistant
Staphylococcus aureus, though it has some adverse effects, including nephrotoxicity, that …

[PDF][PDF] Thymoquinone and curcumin prevent gentamicin-induced liver injury by attenuating oxidative stress, inflammation and apoptosis

SR Galaly, OM Ahmed, AM Mahmoud - J Physiol Pharmacol, 2014 - jpp.krakow.pl
This study was conducted to assess the preventive effect of two plant constituents,
thymoquinone and curcumin, on gentamicin-induced deleterious effect on liver function …

Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

C Caglayan, FM Kandemir, E Darendelioğlu… - Journal of Trace …, 2019 - Elsevier
Objective Mercury is a global environmental pollutant and is responsible for several organ
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …

Rutin attenuates vancomycin-induced nephrotoxicity by ameliorating oxidative stress, apoptosis, and inflammation in rats

S Qu, C Dai, F Lang, L Hu, Q Tang… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Nephrotoxicity is the major limiting factor for the clinical use of vancomycin (VCM) for
treatment of serious infections caused by multiresistant Gram-positive bacteria. This study …

Berberine mitigates cyclophosphamide-induced hepatotoxicity by modulating antioxidant status and inflammatory cytokines

MO Germoush, AM Mahmoud - Journal of cancer research and clinical …, 2014 - Springer
Objectives The present study was designed to investigate the possible protective effects of
berberine against cyclophosphamide (CP)-induced hepatotoxicity in rats. Methods The …

Cinnamic acid ameliorate gentamicin-induced liver dysfunctions and nephrotoxicity in rats through induction of antioxidant activities

E Babaeenezhad, N Nouryazdan, M Nasri… - Heliyon, 2021 - cell.com
This study was the first to evaluate the possible protective effects of cinnamic acid (CA)
against Gentamicin (GM) induced liver and kidney dysfunctions in rats. Adult male Wistar …

Protective effects of thymoquinone on vancomycin-induced nephrotoxicity in rats

F Basarslan, N Yilmaz, S Ates, T Ozgur… - Human & …, 2012 - journals.sagepub.com
Aim: Oxidative stress has been implicated as a potential responsible mechanism in the
pathogenesis of vancomycin (VCM)-induced renal toxicity. Therefore, we aimed to …

[HTML][HTML] Hepatoprotective role of vitexin against cadmium-induced liver damage in male rats: A biochemical, inflammatory, apoptotic and histopathological …

KK Noor, MU Ijaz, N Ehsan, A Tahir, DK Yeni… - Biomedicine & …, 2022 - Elsevier
Cadmium (Cd) is one of the potent occupational and environmental toxicants, which induces
oxidative stress to the multiple organs of the body, including liver. The present investigation …