Objectives This study aimed to determine the role of CD161+ CD4+ T cells in chronic
hepatitis B virus (HBV) infection. Methods A total of 94 patients with chronic hepatitis B …

Given the clinical significance of hepatitis B e antigen (HBeAg) seroconversion in chronic
hepatitis B virus (HBV) infection, it is critical to elucidate the mechanisms regulating this …

Background Hepatitis B virus-related liver fibrosis (HBV-LF) always progresses from
inflammation to fibrosis. However, the relationship between these two pathological …

Immunopathological injury induced by persistent hepatitis B virus (HBV) infection contributes
to the progression from chronic hepatitis B (CHB) to hepatic cirrhosis and hepatocellular …

Background Extensive mononuclear cell infiltration is strongly correlated with liver damage
in patients with chronic hepatitis B virus (CHB) infection. Macrophages and infiltrating …

Abstract Background and Aims Little is known about the mechanisms of IL‐17 secreting T
cells accumulation in HBV‐transfected livers. Here, we investigated the role of the …

Background Chronic hepatitis C virus (HCV) infection causes the skewing and activation of
B cell subsets, but the characteristics of IgG+ B cells in patients with chronic hepatitis C …

Type 3 innate lymphoid cell (ILC3) has recently emerged as a crucial effector in
inflammatory and fibrotic diseases. The present study was designed to determine the roles …

Background & Aims Although CD8+ T cell exhaustion hampers viral control during chronic
HBV infection, the pool of CD8+ T cells is phenotypically and functionally heterogeneous …

Background & Aims During chronic HCV infection, T cell dependent virus-specific antibodies
are produced. However, the role of BT cell interaction in chronic HCV is largely unknown …