Mild traumatic brain injury (mTBI) results in impairment of brain metabolism, which is
propagated by mitochondrial dysfunction in the brain. Mitochondrial dysfunction has been …

Traumatic brain injury (TBI) results in cognitive impairment, which can be long‐lasting after
moderate to severe TBI. Currently, there are no FDA‐approved therapeutics to treat the …

Following experimental traumatic brain injury (TBI), a rapid and significant necrosis occurs at
the site of injury which coincides with significant mitochondrial dysfunction. The present …

Experimental traumatic brain injury (TBI) leads to a rapid and extensive necrosis at the
primary site of injury that appears to be driven in part by significant mitochondrial …

Mild traumatic brain injuries (mTBI), accounting for more than 80% of TBIs, can cause
cognitive and behavioral impairments, the severity and duration of which increase after …

Mitochondrial dysfunction is a pivotal target for neuroprotection strategies for traumatic brain
injury (TBI). However, comprehensive time-course evaluations of mitochondrial dysfunction …

Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide.
The major mechanisms–diffuse axonal injury, cerebral contusion, ischemic neurological …

Traumatic brain injury (TBI) is one of the most prevalent causes of permanent physical and
cognitive disabilities. TBI pathology results from primary insults and a multi‐mechanistic …

Mitochondria constitute a central role in brain energy metabolism, and play a pivotal role in
the development of secondary pathophysiology and subsequent neuronal cell death …

Therapeutic interventions directly targeting processes and mechanisms responsible for
mitochondrial dysfunction, may offer neuroprotection in brain-injured patients. The …