Background Postoperative patient-centred outcome measures are essential to capture the
patient's experience after surgery. Although a large number of pharmacologic opioid …

Introduction For close to a century opioid administration has been a standard of care to
complement anaesthesia during surgery. Considering the worldwide opioid epidemic, this …

Opioids have dominated the management of perioperative pain in recent decades with
higher doses than ever before used in some circumstances. Through the expanding use of …

Background Treatment with opioids is a mainstay in perioperative pain management. While
the leading treatment paradigm has been procedure‐specific pain management, efforts …

Surgical care episodes place opioid-naïve patients at risk for transitioning to new persistent
postoperative opioid use. With one of the central principles being the application of …

The drug-induced, reversible coma of anaesthesia requires three clinical outcomes:
unconsciousness, immobility, and the control of autonomic nervous system (ANS) responses …

EditordAnaesthesiologists have access to a variety of nonopioid analgesics(
dexmedetomidine, dexamethasone, ketamine, lidocaine, etc.). Integrating these drugs into …

Opioids form an important component of general anesthesia and perioperative analgesia.
Discharge opioid prescriptions are identified as a contributor for persistent opioid use and …

Enhanced recovery pathways have quickly become part of the standard of care for patients
undergoing elective surgery, especially in North America and Europe. One of the central …

Background Excessive opioid prescribing after surgery has been recognised as a
contributor to the current crisis of opioid addiction and overdose. Clinicians may potentially …