[HTML][HTML] A new era of antibiotics: the clinical potential of antimicrobial peptides

K Browne, S Chakraborty, R Chen… - International journal of …, 2020 - mdpi.com
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

Antimicrobial peptides under clinical trials

KE Greber, MŦ Dawgul - Current topics in medicinal …, 2017 - ingentaconnect.com
Today microbial drug resistance has become a serious problem not only within inpatient
setting but also within outpatient setting. Repeated intake and unnecessary usage of …

[HTML][HTML] Antimicrobial peptide mimics for clinical use: does size matter?

J Svenson, N Molchanova, CI Schroeder - Frontiers in Immunology, 2022 - frontiersin.org
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Peptide based antimicrobials: Design strategies and therapeutic potential

PK Hazam, R Goyal, V Ramakrishnan - Progress in Biophysics and …, 2019 - Elsevier
Therapeutic activity of antibiotics is noteworthy, as they are used in the treatment of microbial
infections. Regardless of their utility, there has been a steep decrease in the number of drug …

Synergy among antibacterial peptides and between peptides and small-molecule antibiotics

M Cassone, L Otvos Jr - Expert review of anti-infective therapy, 2010 - Taylor & Francis
Antimicrobial peptides are key components of native immunity. Unlike most common small-
molecule antibiotics, antimicrobial peptides have been refined by evolution to work …

Mini review on antimicrobial peptides, sources, mechanism and recent applications

JK Boparai, PK Sharma - Protein and peptide letters, 2020 - ingentaconnect.com
Antimicrobial peptides in recent years have gained increased interest among scientists,
health professionals and the pharmaceutical companies owing to their therapeutic potential …

[HTML][HTML] Molecular engineering of antimicrobial peptides: Microbial targets, peptide motifs and translation opportunities

P Cardoso, H Glossop, TG Meikle, A Aburto-Medina… - Biophysical …, 2021 - Springer
The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …

[HTML][HTML] Antimicrobial peptides: an overview of a promising class of therapeutics

A Giuliani, G Pirri, S Nicoletto - Open Life Sciences, 2007 - degruyter.com
Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …

Antimicrobial peptides: a promising therapeutic strategy in tackling antimicrobial resistance

R Nuti, NS Goud, AP Saraswati… - Current medicinal …, 2017 - ingentaconnect.com
Background: Antimicrobial resistance (AMR) has posed a serious threat to global public
health and it requires immediate action, preferably long term. Current drug therapies have …

[HTML][HTML] Multifunctional antimicrobial peptides: therapeutic targets in several human diseases

M Zaiou - Journal of Molecular Medicine, 2007 - Springer
Antimicrobial peptides have emerged as promising agents against antibiotic-resistant
pathogens. They represent essential components of the innate immunity and permit humans …