Voltage-gated potassium (Kv) channels in the KCNQ (Kv7) family are essential features of a
broad range of excitable and non-excitable cell types and are found in organisms ranging …

Since prehistory, human species have depended on plants for both food and medicine.
Even in countries with ready access to modern medicines, alternative treatments are still …

Ion channels are essential for basic cellular function and for processes including sensory
perception and intercellular communication in multicellular organisms. Voltage-gated …

Botanical folk medicines have been used throughout human history to treat common
disorders such as hypertension, often with unknown underlying mechanisms. Here, we …

Many commonly consumed plants are used as folk medicines, often with unclear molecular
mechanisms. Recent studies uncovered the ubiquitous and influential KCNQ family of …

The voltage-gated KCNQ1 (KvLQT1, Kv7. 1) potassium channel plays a crucial role in
shaping the cardiac action potential as well as in controlling the water and salt homeostasis …

KCNQ2 and KCNQ3, both of which are mutated in a type of human neonatal epilepsy, form
heteromeric potassium channels that are expressed in broad regions of the brain. The …

Voltage-gated potassium (Kv) channels in the KCNQ subfamily serve essential roles in the
nervous system, heart, muscle and epithelia. Different heteromeric KCNQ complexes likely …

Kv7 channels are voltage-gated potassium channels encoded by KCNQ genes that have a
considerable physiological impact in many cell types. This reliance upon Kv7 channels for …

Voltage-gated potassium (Kv) channels extend their functional repertoire by coassembling
with MinK-related peptides (MiRPs). MinK slows the activation of channels formed with …