Ischemic stroke triggers endogenous angiogenic mechanisms, which correlates with longer
survival in patients. As such, promoting angiogenesis appears to be a promising approach …

Neurons in the penumbra (the area surrounding ischemic tissue that consists of still viable
tissue but with reduced blood flow and oxygen transport) may be rescued following stroke if …

The breakdown of the blood–brain barrier (BBB) is a critical event in the development of
secondary brain injury after stroke. Among the cellular hallmarks in the acute phase after …

Vascular endothelial growth factor (VEGF) is a pleiotropic growth factor that is crucially
involved in neurovascular remodeling in the ischemic brain. VEGF promotes angiogenesis …

Based on its trophic influence on neurons and vascular cells, vascular endothelial growth
factor (VEGF) is a promising candidate for stroke treatment. VEGF's survival-promoting …

Vascular endothelial growth factor (VEGF) is involved in many central nervous system
disorders, including stroke, and confers neuroprotection in cerebral ischemia. In this Mini …

The process of angiogenesis is paramount in blood vessel recovery and regeneration after a
cerebrovascular accident. The reparative role of angiogenesis in the maintenance of brain …

Therapeutic angiogenesis with vascular endothelial growth factor (VEGF) is a clinically
promising strategy in ischaemic disease. The pathophysiological consequences of …

Vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang1) were originally
identified as endothelial-specific ligands regulating key functions of the vasculature …

Disruption of the blood-brain barrier (BBB) integrity occurring during the early onset of stroke
is not only a consequence of, but also contributes to the further progression of stroke …