68Ga‐PET: a powerful generator‐based alternative to cyclotron‐based PET radiopharmaceuticals

M Fani, JP André, HR Maecke - Contrast media & molecular …, 2008 - Wiley Online Library
PET (positron emission tomography) is a powerful diagnostic and imaging technique which
requires short‐lived positron emitting isotopes. The most commonly used are accelerator …

68Ga-PET Radiopharmacy: A Generator-Based Alternative to 18F-Radiopharmacy

HR Maecke, JP André - PET chemistry: the driving force in molecular …, 2007 - Springer
Positron emission tomography (PET) is becoming a dominating method in the field of
molecular imaging. Most commonly used radionuclides are accelerator produced 11 C and …

The untapped potential of Gallium 68-PET: The next wave of 68Ga-agents

DL Smith, WAP Breeman, J Sims-Mourtada - Applied Radiation and …, 2013 - Elsevier
68Gallium-PET (68Ga-PET) agents have significant clinical promise. The radionuclide can
be produced from a 68Ge/68Ga generator on site and is a convenient alternative to …

[HTML][HTML] Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling

MI Tsionou, CE Knapp, CA Foley, CR Munteanu… - RSC …, 2017 - pubs.rsc.org
Gallium-68 (68Ga) is a positron-emitting isotope used for clinical PET imaging of peptide
receptor expression. 68Ga radiopharmaceuticals used in molecular PET imaging consist of …

Convenient Preparation of 68Ga-Based PET-Radiopharmaceuticals at Room Temperature

I Velikyan, H Maecke, B Langstrom - Bioconjugate chemistry, 2008 - ACS Publications
A straightforward labeling using generator produced positron emitting 68Ga, which provides
high quality images, may result in kit type production of PET radiopharmaceuticals and make …

Microwave-Supported Preparation of 68Ga Bioconjugates with High Specific Radioactivity

I Velikyan, GJ Beyer, B Långström - Bioconjugate chemistry, 2004 - ACS Publications
The generator-produced positron-emitting 68Ga (T 1/2= 68 min) is of potential interest for
clinical PET. 68Ga as a metallic cation is suitable for complexation reactions with chelators …

The renaissance of the 68Ge/68Ga radionuclide generator initiates new developments in 68Ga radiopharmaceutical chemistry

F Roesch, PJ Riss - Current topics in medicinal chemistry, 2010 - ingentaconnect.com
68Ge/68Ga radionuclide generators have been investigated for almost fifty years now, since
the cyclotronindependent availability of positron emitting 68Ga via the 68Ge/68Ga system …

Processing of generator-produced 68Ga for medical application

KP Zhernosekov, DV Filosofov, RP Baum… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The 68Ge/68Ga generator provides an excellent source of positron-emitting 68Ga. However,
newly available “ionic” 68Ge/68Ga radionuclide generators are not necessarily optimized for …

Recent Breakthrough in 68Ga-Radiopharmaceuticals Cold Kits for Convenient PET Radiopharmacy

D Satpati - Bioconjugate Chemistry, 2021 - ACS Publications
68Ga-PET has emerged as an important diagnostic tool for precise detection and monitoring
of oncological situations. Availability, cost, and radiosynthesis procedure are determining …

68Ga-labelled DOTA-derivatised peptide ligands

GJ Meyer, H Mäcke, J Schuhmacher… - European journal of …, 2004 - Springer
Abstract 68 Ge/68 Ga generators provide cyclotron-independent access to positron emission
tomography (PET) radiopharmaceuticals. We describe a system which allows the safe and …