[HTML][HTML] Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach
A Bonnefond, L Yengo, A Dechaume, M Canouil… - BMC medicine, 2017 - Springer
Background Salivary (AMY1) and pancreatic (AMY2) amylases hydrolyze starch. Copy
number of AMY1A (encoding AMY1) was reported to be higher in populations with a high …
number of AMY1A (encoding AMY1) was reported to be higher in populations with a high …
[HTML][HTML] Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children
MA Mejía-Benítez, A Bonnefond, L Yengo, M Huyvaert… - Diabetologia, 2015 - Springer
Aims/hypothesis Childhood obesity is a major public health problem in Mexico, affecting one
in every three children. Genome-wide association studies identified genetic variants …
in every three children. Genome-wide association studies identified genetic variants …
[HTML][HTML] Dietary starch intake modifies the relation between copy number variation in the salivary amylase gene and BMI
G Rukh, U Ericson, J Andersson-Assarsson… - The American journal of …, 2017 - Elsevier
Background Studies have shown conflicting associations between the salivary amylase
gene (AMY1) copy number and obesity. Salivary amylase initiates starch digestion in the …
gene (AMY1) copy number and obesity. Salivary amylase initiates starch digestion in the …
Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes
D Carpenter, S Dhar, LM Mitchell, B Fu… - Human molecular …, 2015 - academic.oup.com
The human salivary amylase genes display extensive copy number variation (CNV), and
recent work has implicated this variation in adaptation to starch-rich diets, and in association …
recent work has implicated this variation in adaptation to starch-rich diets, and in association …
Metabolomic profile of low–copy number carriers at the salivary α-amylase gene suggests a metabolic shift toward lipid-based energy production
A Arredouani, M Stocchero, N Culeddu… - Diabetes, 2016 - Am Diabetes Assoc
Low serum salivary amylase levels have been associated with a range of metabolic
abnormalities, including obesity and insulin resistance. We recently suggested that a low …
abnormalities, including obesity and insulin resistance. We recently suggested that a low …
Human amylase gene copy number variation as a determinant of metabolic state
PJD Elder, DB Ramsden, D Burnett… - Expert Review of …, 2018 - Taylor & Francis
Introduction: Humans have multiple genes encoding amylase that are broadly divided into
salivary (AMY1) and pancreatic (AMY2) genes. They exhibit some of the greatest copy …
salivary (AMY1) and pancreatic (AMY2) genes. They exhibit some of the greatest copy …
High AMY1 copy number protects against obesity in Portuguese young adults
Background: The highly polymorphic copy number variation (CNV) in the salivary amylase
gene (AMY1) has been associated with obesity in different populations. However, some …
gene (AMY1) has been associated with obesity in different populations. However, some …
Starch digestion–related amylase genetic variant affects 2-year changes in adiposity in response to weight-loss diets: the POUNDS lost trial
Salivary and pancreatic amylases (encoded by AMY1 and AMY2 genes, respectively) are
responsible for digesting starchy foods. AMY1 and AMY2 show copy number variations that …
responsible for digesting starchy foods. AMY1 and AMY2 show copy number variations that …
[HTML][HTML] Increased Inflammation and Cardiometabolic Risk in Individuals with Low AMY1 Copy Numbers
C Marquina, A Mousa, R Belski, H Banaharis… - Journal of Clinical …, 2019 - mdpi.com
Lower copy number variations (CNVs) in the salivary amylase gene (AMY1) have been
associated with obesity and insulin resistance; however, the relationship between AMY1 …
associated with obesity and insulin resistance; however, the relationship between AMY1 …
[HTML][HTML] Low serum amylase and obesity, diabetes and metabolic syndrome: A novel interpretation
K Nakajima - World journal of diabetes, 2016 - ncbi.nlm.nih.gov
For the last decade, low serum amylase (hypoamylasemia) has been reported in certain
common cardiometabolic conditions such as obesity, diabetes (regardless of type), and …
common cardiometabolic conditions such as obesity, diabetes (regardless of type), and …