Page 1 frontiers Research Topics Fibrosis: Etiology, pathophysiology, measurements, and
therapy Edited by Yuxia Zhao, Panpan Hao, Peizhe Wang, Fujian Lu and Yanping Liu …

As we enter into this new era of molecular medicine with an expanding body of knowledge
related to the molecular pathogenesis of human disease and an increasing recognition of …

Cardiac fibrosis is a significant global health problem that is closely associated with multiple
forms of cardiovascular disease, including myocardial infarction, dilated cardiomyopathy …

Organ fibrosis is a very common condition affecting different organs and tissues following
chronic tissue injury. Organ fibrosis can be defined as an excess deposition of fibrillar …

Fibrosis is a prevalent and detrimental condition associated with various diseases with a
high impact on global morbidity and mortality rates. Despite its diverse causes and affected …

Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the
industrialized world. It has long been thought to be relentlessly progressive and irreversible …

Cardiomyopathies are a group of diseases characterized by abnormalities in structure and
function of the heart muscles (Abelmann, Prog Cardiovasc Dis. 1984; 27: 73–94). The …

Fibrosis can lead to a broad range of diseases affecting essentially every organ. Thus,
interventions targeting fibrosis are expected to have profound therapeutic effects. However …

Cardiac fibrosis is characterized by net accumulation of extracellular matrix proteins in the
cardiac interstitium, and contributes to both systolic and diastolic dysfunction in many …

The hallmark of a variety of fibrotic diseases such as liver fibrosis, lung fibrosis, skin fibrosis
and atherosclerosis is extensive extracellular matrix remodeling (ECMr) of the disease …