This in silico toxicogenomic analysis aims to:(i) testify the hypothesis about the influence of
the environmentally relevant toxic metals (lead, methylmercury (organic form of mercury) …

Neurological disorders have attracted considerable attention in the last decades owing to
their large burden on global health. Currently, about 100 million people worldwide are …

The environment has been implicated to be a strong determinant of brain health with higher
risk of neurodegeneration. The drastic rise in the prevalence of neurodegenerative diseases …

Parkinson's disease (PD) is a neurodegenerative condition characterized by the dopamine
(DA) neuronal loss in the substantia nigra. PD impairs motor controls symptoms such as …

Neurodegenerative disorders are typically sporadic in nature in addition to usually
influenced through an extensive range of environmental factors, lifestyle, and genetic …

Conventional toxicological risk assessment methods mainly working on single chemicals
that fail to adequately address the simultaneous exposure and their potential toxicity in …

Industrialization era is considered as a part of important human development.
Industrialization increases the extensive use of different metals from earth crust because of …

Biologically important metals regulate cellular homeostasis in living systems. Anthropogenic
exposure to these metals can cause adverse effects, including an increased incidence of …

Chronic exposure to heavy metals such as Pb, As, and MeHg can be associated with an
increased risk of developing neurodegenerative diseases. Our in vitro bioassays results …

In the last few years, neurodegenerative diseases like Alzheimer's disease (AD) and
Parkinson's disease (PD) have attracted attention due to their high prevalence worldwide …