TGF-ẞ is a member of a large family of cytokines with a crucial role in embryonic
development and tissue homeostasis. Disruption of the TGF-B signaling pathway has been …

Transforming growth factor-ß (TGF-ß) has pleiotropic effects on a wide variety of cell types. It
is essential for cellular homeostasis and has both tumor-inhibiting and tumor-promoting …

The name transforming growth factor-ẞ (TGF-ẞ) has come to represent a family of highly
homologous polypeptides with a wide range of biological activities. The first member of this …

The TGFß pathway has recently emerged as a putative therapeutic target against cancer.
However, TGFß has a complex and dual role in cancer. In normal epithelial cells and early …

Cancer stem cells are tumor cells characterized by their ability to induce tumorigenesis and
to self-renew. Recent research advance in cancer research field has demonstrated …

Transforming growth factor-ẞ (TGF-ß) is a potent growth inhibitor endowed with
tumorsuppressing activity. Unfortunately, cancers are often resistant to such growth …

Transforming growth factor-β (TGF-β), an extensively investigated cytokine, plays a very
important role in promoting the spread of cancers in the body, and can play a direct role in …

Transforming growth factor β (TGFβ) is a multifunctional cytokine, and its signalling
responses are exerted via integrated intracellular pathways and complex regulatory …

More than 30 years after its dis-covery, transforming growth factor ß (TGF-ß) engages
developmental biologists, immunologists, cell biologists, and cancer researchers. New …