[HTML][HTML] Hirsutine, an emerging natural product with promising therapeutic benefits: a systematic review

MS Bhuia, P Wilairatana, J Ferdous, R Chowdhury… - Molecules, 2023 - mdpi.com
Fruits and vegetables are used not only for nutritional purposes but also as therapeutics to
treat various diseases and ailments. These food items are prominent sources of …

Molecular targets and anticancer potential of sanguinarine—A benzophenanthridine alkaloid

S Galadari, A Rahman, S Pallichankandy… - Phytomedicine, 2017 - Elsevier
Background Cancer is an enormous global health burden, and should be effectively
addressed with better therapeutic strategies. Currently, over 60% of the clinically approved …

[HTML][HTML] Pharmacological basis of tanshinone and new insights into tanshinone as a multitarget natural product for multifaceted diseases

Z Li, J Zou, D Cao, X Ma - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Drug development has long included the systematic exploration of various resources.
Among these, natural products are one of the most important resources from which novel …

Thymoquinone, an active compound of Nigella sativa: role in prevention and treatment of cancer

SA Almatroodi, A Almatroudi, MA Alsahli… - Current …, 2020 - ingentaconnect.com
Background: Cancer is the leading cause of death worldwide and the current mode of
cancer treatment causes side effects on normal cells and are still the key challenges in its' …

Hispidulin: A novel natural compound with therapeutic potential against human cancers

A Ashaq, MF Maqbool, A Maryam, M Khan… - Phytotherapy …, 2021 - Wiley Online Library
Cancer is one of the most devastating disease and leading cause of death worldwide. The
conventional anticancer drugs are monotarget, toxic, expensive and suffer from drug …

Isoliquiritigenin (ISL) and its formulations: potential antitumor agents

TT Zhao, YQ Xu, HM Hu, HB Gong… - Current Medicinal …, 2019 - ingentaconnect.com
Isoliquiritigenin (2', 4', 4-trihydroxychalcone, ISL) is one of the most important chalcone
compounds which is mainly derived from licorice root and many other plants. It exhibits a …

[HTML][HTML] Genkwanin: An emerging natural compound with multifaceted pharmacological effects

N El Menyiy, S Aboulaghras, S Bakrim… - Biomedicine & …, 2023 - Elsevier
Plant bioactive molecules could play key preventive and therapeutic roles in chronological
aging and the pathogenesis of many chronic diseases, often accompanied by increased …

Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

S Singh, N Pathak, E Fatima, AS Negi - European Journal of Medicinal …, 2021 - Elsevier
Alkaloids are one of the most important classes of plant bioactives. Among these
isoquinoline alkaloids possess varied structures and exhibit numerous biological activities …

Anticancer potential of sanguinarine for various human malignancies

IW Achkar, F Mraiche, RM Mohammad… - Future medicinal …, 2017 - Future Science
Sanguinarine (Sang)–a benzophenanthridine alkaloid extracted from Sanguinaria
canadensis–exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory …

Sanguinarine inhibits the proliferation of BGC-823 gastric cancer cells via regulating miR-96-5p/miR-29c-3p and the MAPK/JNK signaling pathway

XZ Dong, Y Song, YP Lu, Y Hu, P Liu… - Journal of natural …, 2019 - Springer
Sanguinarine (SAN), a quaternary benzophenanthridine alkaloid extracted from the root of
Papaveraceae plants, has shown antitumour effects in multiple cancer cells. However, the …