The role of immune semaphorins in the pathogenesis of multiple sclerosis: Potential therapeutic targets
The immune and nervous systems possess a highly intricate network of synaptic
connections, shared messenger molecules, and exquisite communication ways, allowing …
connections, shared messenger molecules, and exquisite communication ways, allowing …
[HTML][HTML] The role of immune semaphorins in multiple sclerosis
T Okuno, Y Nakatsuji, A Kumanogoh - FEBS letters, 2011 - Elsevier
The nervous and immune systems have similar functional characteristics. Both have an
intricate network of synaptic connections and an exquisite communication system that …
intricate network of synaptic connections and an exquisite communication system that …
Semaphorins 3A and 7A: potential immune and neuroregenerative targets in multiple sclerosis
H Eixarch, A Gutiérrez-Franco, X Montalban… - Trends in molecular …, 2013 - cell.com
Semaphorins have been classically defined as axonal signalling cues involved in central
nervous system (CNS) development, but in adults these molecules are expressed in distinct …
nervous system (CNS) development, but in adults these molecules are expressed in distinct …
Semaphorin 7A as a potential therapeutic target for multiple sclerosis
A Gutiérrez-Franco, H Eixarch, C Costa, V Gil… - Molecular …, 2017 - Springer
Abstract Semaphorin 7A (sema7A) is classified as an immune semaphorin with dual
functions in the immune system and in the central nervous system (CNS). These molecules …
functions in the immune system and in the central nervous system (CNS). These molecules …
The role of semaphorin family in immune systems
D Ito, S Nojima, A Kumanogoh - Nihon Rinsho Men'eki Gakkai …, 2014 - europepmc.org
Semaphorins are soluble and membrane-bound proteins originally identified as axonal
growth cone-collapsing guidance molecules which are involved in the development of the …
growth cone-collapsing guidance molecules which are involved in the development of the …
Biology and function of neuroimmune semaphorins 4A and 4D
EH Nkyimbeng-Takwi, SP Chapoval - Immunologic research, 2011 - Springer
Semaphorins belong to a family of membrane-bound and secreted molecules that regulate
the functional activity of axons in the nervous system. Sema4A and Sema4D were the first …
the functional activity of axons in the nervous system. Sema4A and Sema4D were the first …
Immune semaphorins: novel features of neural guidance molecules
M Mizui, A Kumanogoh, H Kikutani - Journal of clinical immunology, 2009 - Springer
Introduction The immune and nervous system have various common features in the
functional characteristics. Both have an intricate network of synaptic connections and an …
functional characteristics. Both have an intricate network of synaptic connections and an …
Differential expression of sema3A and sema7A in a murine model of multiple sclerosis: Implications for a therapeutic design
A Gutiérrez-Franco, C Costa, H Eixarch, M Castillo… - Clinical …, 2016 - Elsevier
We characterised the expression of semaphorin (sema) 3A, sema7A and their receptors in
the immune and the central nervous system (CNS) at different stages of experimental …
the immune and the central nervous system (CNS) at different stages of experimental …
Roles of the semaphorin family in immune regulation.
A Kumanogoh, H Kikutani - Advances in immunology, 2003 - europepmc.org
The immune system and the nervous system have distinct roles in maintaining physiological
homeostasis. These independent systems, however, influence each other while sharing …
homeostasis. These independent systems, however, influence each other while sharing …
Neuronal semaphorins regulate a primary immune response
S Moretti, A Procopio, M Boemi… - Current neurovascular …, 2006 - ingentaconnect.com
Semaphorins are involved in a wide range of biological processes, including axon
guidance, neuronal migration, angiogenesis, cardio-and osteo-genesis. Recently they have …
guidance, neuronal migration, angiogenesis, cardio-and osteo-genesis. Recently they have …