Statins, known as HMG-CoA reductase (HMGCR) inhibitors, have primarily been utilized for
metabolic and angiographic medical applications because of their cholesterol-lowering …

The beneficial effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase
inhibitors (statins) on coronary events have generally been attributed to their …

Statins are the most efficacious hypolipidemic drugs available. Numerous meta-analyses of
clinical trials have provided unequivocal evidence that statins are effective and safe in …

Statins are a class of drugs widely used worldwide to manage hypercholesterolemia and the
prevention of secondary heart attacks. Currently, available statins vary in terms of their …

BACKGROUND: The role of statin drugs in the reduction of serum lipids has been well
documented. More recently, evidence suggesting that statins may positively impact many …

Background Apart from reducing the circulating LDL-c and the number of cardiovascular
cases as well as fatalities, statins have auxiliary non–lipid-related or cholesterol …

Statins or 3-hydroxy-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors not only
prevents the synthesis of cholesterol biosynthesis but also inhibits the synthesis of essential …

Long-and short-term trials with the 3-hydroxy-3-methylglutaryl coenzyme A reductase
inhibitors (statins) have demonstrated significant reductions in cardiovascular events in …

The HMG Co-enzyme inhibitors and new lipid-modifying agents expand their new
therapeutic target options in the field of medical profession. Statins have been described as …

Clinical trials have firmly established that 3-hydroxy-3-methylglutaryl coenzyme A (HMG-
CoA) reductase inhibitors (statins) can induce the regression of vascular atherosclerosis and …