The extracellular matrix (ECM) consists of a complex mixture of structural and functional
proteins and serves an important role in tissue and organ morphogenesis, maintenance of …

The principles and ultimate goals of regenerative medicine and developmental biology
involve a complex sequence of events, culminating in the formation of structurally and …

During normal morphogenesis the extracellular matrix (ECM) influences cell motility,
proliferation, apoptosis, and differentiation. Tissue engineers have attempted to harness the …

The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

The extracellular matrix is a complex, dynamic and critical component of all tissues. It
functions as a scaffold for tissue morphogenesis, provides cues for cell proliferation and …

Contributing to organ formation and tissue regeneration, extracellular matrix (ECM)
constituents provide tissue with three-dimensional (3D) structural integrity and cellular …

The extracellular matrix (ECM) serves diverse functions and is a major component of the
cellular microenvironment. The ECM is a highly dynamic structure, constantly undergoing a …

The extracellular matrix (ECM) is an essential feature of development, tissue homeostasis
and recovery from injury. How the ECM responds dynamically to cellular and soluble …

Highlights•ECM signaling in morphogenesis and tissue repair.•ECM signals with
mechanically liberated or exposed biologically active sites.•ECM signals via proteolysis or …

Bioscaffolds derived from xenogeneic extracellular matrix (ECM) have been used in
numerous tissue engineering applications. The safety and efficacy of such scaffolds when …