Investigating the effect of tyrosine kinase inhibitors on the interaction between human serum albumin by atomic force microscopy

Y Fu, J Wang, Y Wang, H Sun - Biomolecules, 2022 - mdpi.com
It is important for elucidating the regulation mechanism of life activities, as well as for the
prevention, diagnosis, and drug design of diseases, to study protein–protein interactions …

Evaluating interaction forces between BSA and rabbit anti-BSA in sulphathiazole sodium, tylosin and levofloxacin solution by AFM

C Wang, J Wang, L Deng - Nanoscale research letters, 2011 - Springer
Protein-protein interactions play crucial roles in numerous biological processes. However, it
is still challenging to evaluate the protein-protein interactions, such as antigen and antibody …

Evaluating the effect of aminoglycosides on the interaction between bovine serum albumins by atomic force microscopy

Y Wang, J Wang, S Huang, C Liu, Y Fu - International journal of biological …, 2019 - Elsevier
Abstract Characterization and determination of protein-protein interactions (PPIs) plays an
important role in molecular biological science. In this study, the effect of aminoglycosides …

Study on Specific and Non-Specific Interactions Between BSA and Anti-BSA in Fluoroquinolone Antibiotic Solution by AFM

Y Wang, J Wang, J Sun, Y Xie, C Liu… - … of Nanoscience and …, 2019 - ingentaconnect.com
Most of the physiological activities of organisms are realized by protein–protein interactions
(PPIs), which are one of the fundamental research fields in biomedicine. Investigation of …

Evaluation of medicine effects on the interaction of myoglobin and its aptamer or antibody using atomic force microscopy

Q Wang, L Liu, X Yang, K Wang, N Chen… - Analytical …, 2015 - ACS Publications
The effects of medicine on the biomolecular interaction have been given increasing attention
in biochemistry and affinity-based analytics since the environment in vivo is complex …

Elucidation of binding dynamics of tyrosine kinase inhibitor tepotinib, to human serum albumin, using spectroscopic and computational approach

M Amir, S Javed - International Journal of Biological Macromolecules, 2023 - Elsevier
Tepotinib (TPT), an anticancer drug, is a fibroblast growth factor receptor inhibitor approved
by the FDA for the chemotherapy of urothelial carcinoma. The binding of anticancer …

Experimental and in silico investigation on the interaction of indomethacin with bovine serum albumin: Effect of sodium dodecyl sulfate surfactant monomers on the …

MS Ali, J Muthukumaran, M Jain, ASS Al-Sanea… - Journal of Molecular …, 2021 - Elsevier
This paper describes the interaction of indomethacin with bovine serum albumin (BSA)
using experimental and computational approaches. Inner filter effect (IFE) had significantly …

Experimental approaches and computational modeling of rat serum albumin and its interaction with piperine

G Zazeri, APR Povinelli, MF Lima… - International journal of …, 2019 - mdpi.com
The bioactive piperine (1-piperoyl piperidine) compound found in some pepper species
(Piper nigrum linn and Piper sarmentosum Roxb) has been shown to have therapeutic …

Chip‐based protein–protein interaction studied by atomic force microscopy

FS Kao, W Ger, YR Pan, HC Yu… - Biotechnology and …, 2012 - Wiley Online Library
In this article, a technique for accurate direct measurement of protein‐to‐protein interactions
before and after the introduction of a drug candidate is developed using atomic force …

Exploring the energy profile of human IgG/rat anti-human IgG interactions by dynamic force spectroscopy

Z Lv, J Wang, G Chen - The Protein Journal, 2012 - Springer
Interactions between antibody and antigen molecules play essential roles in biological
recognition processes as well as medical diagnosis. Therefore, an understanding of the …