Diversity and population-genetic properties of copy number variations and multicopy genes in cattle

DM Bickhart, L Xu, JL Hutchison, JB Cole… - DNA …, 2016 - academic.oup.com
The diversity and population genetics of copy number variation (CNV) in domesticated
animals are not well understood. In this study, we analysed 75 genomes of major taurine …

Copy number variation of individual cattle genomes using next-generation sequencing

DM Bickhart, Y Hou, SG Schroeder, C Alkan… - Genome …, 2012 - genome.cshlp.org
Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in
or near segmental duplication regions are often intractable. Using a read depth approach …

Evolutionary and functional features of copy number variation in the cattle genome

BN Keel, AK Lindholm-Perry, WM Snelling - Frontiers in genetics, 2016 - frontiersin.org
Genomic structural variations are an important source of genetic diversity. Copy number
variations (CNVs), gains and losses of large regions of genomic sequence between …

Analysis of copy number variations among diverse cattle breeds

GE Liu, Y Hou, B Zhu, MF Cardone, L Jiang… - Genome …, 2010 - genome.cshlp.org
Genomic structural variation is an important and abundant source of genetic and phenotypic
variation. Here, we describe the first systematic and genome-wide analysis of copy number …

Analysis of copy number variants in the cattle genome

JW Kijas, W Barendse, W Barris, B Harrison… - Gene, 2011 - Elsevier
Copy number variation (CNV) is likely to be an important component of heritable variation in
livestock. To characterise CNVs in cattle, we performed a genome wide survey to determine …

Diversity of copy number variation in the worldwide goat population

M Liu, Y Zhou, BD Rosen, CP Van Tassell, A Stella… - Heredity, 2019 - nature.com
Goats (Capra hircus) are an important farm animal species. Copy number variation (CNV)
represents a major source of genomic structural variation. We investigated the diversity of …

Landscape of copy number variations in Bos taurus: individual – and inter-breed variability

M Mielczarek, M Frąszczak, E Nicolazzi, JL Williams… - BMC genomics, 2018 - Springer
Background The number of studies of Copy Number Variation in cattle has increased in
recent years. This has been prompted by the increased availability of data on …

A survey of copy number variation in the porcine genome detected from whole-genome sequence

BN Keel, DJ Nonneman, AK Lindholm-Perry… - Frontiers in …, 2019 - frontiersin.org
Copy number variations (CNVs) are gains and losses of large regions of genomic sequence
between individuals of a species. Although CNVs have been associated with various …

Detection of copy number variations and their effects in Chinese bulls

L Zhang, S Jia, M Yang, Y Xu, C Li, J Sun, Y Huang… - BMC genomics, 2014 - Springer
Abstract Background Copy number variations (CNVs) are a main source of genomic
structural variations underlying animal evolution and production traits. Here, with one pure …

Population-genetic properties of differentiated copy number variations in cattle

L Xu, Y Hou, DM Bickhart, Y Zhou, EHA Hay, J Song… - Scientific reports, 2016 - nature.com
While single nucleotide polymorphism (SNP) is typically the variant of choice for population
genetics, copy number variation (CNV) which comprises insertion, deletion and duplication …