Metabolic actions of kisspeptin signaling: Effects on body weight, energy expenditure, and feeding
AD Hudson, AS Kauffman - Pharmacology & therapeutics, 2022 - Elsevier
Kisspeptin (encoded by the Kiss1 gene) and its receptor, KISS1R (encoded by the Kiss1r
gene), have well-established roles in stimulating reproduction via central actions on …
gene), have well-established roles in stimulating reproduction via central actions on …
[HTML][HTML] The role of kisspeptin neurons in reproduction and metabolism
CJL Harter, GS Kavanagh… - Journal of …, 2018 - joe.bioscientifica.com
Kisspeptin is a neuropeptide with a critical role in the function of the hypothalamic–pituitary–
gonadal (HPG) axis. Kisspeptin is produced by two major populations of neurons located in …
gonadal (HPG) axis. Kisspeptin is produced by two major populations of neurons located in …
Novel actions of kisspeptin signaling outside of GnRH-mediated fertility: a potential role in energy balance
R Patel, JT Smith - Domestic Animal Endocrinology, 2020 - Elsevier
Kisspeptin, encoded by Kiss1 gene expressing neurons in the hypothalamus, is a requisite
for fertility and now appears critical in the regulation of energy balance. Kisspeptin neurons …
for fertility and now appears critical in the regulation of energy balance. Kisspeptin neurons …
Metabolic regulation of kisspeptin
JM Castellano, M Tena-Sempere - Kisspeptin signaling in reproductive …, 2013 - Springer
Body energy balance and metabolic signals are important modulators of puberty and
reproductive function, so that perturbations of metabolism and energy reserves (ranging …
reproductive function, so that perturbations of metabolism and energy reserves (ranging …
Emerging roles for kisspeptin in metabolism
C Izzi‐Engbeaya, WS Dhillo - The Journal of Physiology, 2022 - Wiley Online Library
Kisspeptin, a neuropeptide hormone, has been firmly established as a key regulator of the
hypothalamic–pituitary–gonadal axis and mammalian reproductive behaviour. In recent …
hypothalamic–pituitary–gonadal axis and mammalian reproductive behaviour. In recent …
Gonadal hormone-dependent vs.-independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis
I Velasco, S León, A Barroso, F Ruiz-Pino, V Heras… - Metabolism, 2019 - Elsevier
Abstract Background Kisspeptins, encoded by Kiss1, have emerged as essential regulators
of puberty and reproduction by primarily acting on GnRH neurons, via their canonical …
of puberty and reproduction by primarily acting on GnRH neurons, via their canonical …
[HTML][HTML] Conditional knockout of kisspeptin signaling in brown adipose tissue increases metabolic rate and body temperature and lowers body weight
KP Tolson, N Marooki, P Julie-Ann… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
The peptide kisspeptin and its receptor, Kiss1r, act centrally to stimulate reproduction.
Evidence indicates that kisspeptin signaling is also important for body weight (BW) and …
Evidence indicates that kisspeptin signaling is also important for body weight (BW) and …
[HTML][HTML] Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity
The neuropeptide kisspeptin regulates reproduction by stimulating gonadotropin-releasing
hormone (GnRH) neurons via the kisspeptin receptor KISS1R. In addition to GnRH neurons …
hormone (GnRH) neurons via the kisspeptin receptor KISS1R. In addition to GnRH neurons …
[HTML][HTML] The emerging role (s) for kisspeptin in metabolism in mammals
A Wolfe, MA Hussain - Frontiers in Endocrinology, 2018 - frontiersin.org
Kisspeptin was initially identified as a metastasis suppressor. Shortly after the initial
discovery, a key physiologic role for kisspeptin emerged in the regulation of fertility, with …
discovery, a key physiologic role for kisspeptin emerged in the regulation of fertility, with …
There is kisspeptin–and then there is kisspeptin
MA Hussain, WJ Song, A Wolfe - Trends in Endocrinology & Metabolism, 2015 - cell.com
While kisspeptin was initially found to function as a metastasis suppressor, after
identification of its receptor KISS1R and their expression profiles in tissues such as the …
identification of its receptor KISS1R and their expression profiles in tissues such as the …
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