This study investigated the response of acute lymphoblastic leukaemia (ALL) cells to Wnt
proteins. Accumulation of β‐catenin was measured by Western blotting and …

Acute lymphoblastic leukaemia (ALL) is the most common malignancy in children. Recently,
there has been a growing interest in Wnt signalling in several aspects of cellular …

The β-catenin protein is at the core of the canonical Wnt signalling pathway. Wnt stimulation
leads to β-catenin accumulation, nuclear translocation and interaction with T-cell …

Background: Wnt/β-catenin signaling is involved in the growth of various types of cancer
cells. Wnt3A has been reported to promote the self-renewal of hematopoietic stem cells …

WNT signaling has been implicated in the regulation of hematopoietic stem cells and plays
an important role during T-cell development in thymus. Here we investigated WNT pathway …

The Wnt/β-catenin pathway plays a significant role in several aspects of cell biology,
including the stimulation of gene expression, growth, and mobility. Wnt proteins activate at …

Acute lymphoblastic leukemia (ALL) is an aggressive hematologic neoplastic disorder that
arises from the clonal expansion of transformed T-cell or B-cell precursors. Thanks to …

Wnt signaling plays an important role in stem cell self-renewal and proliferation. Aberrant
activation of Wnt signaling and its downstream targets are intimately linked with several …

Activation of the Wnt/β-catenin signaling pathway is a hallmark of a number of solid tumors.
We analyzed the regulation of the Wnt/β-catenin pathway in acute lymphoblastic leukemia …

Acute myeloid leukaemia (AML) is a group of malignant diseases of the haematopoietic
system. AML occurs as the result of mutations in haematopoietic stem/progenitor cells, which …