The good and evil of complement activation in HIV-1 infection

Q Yu, R Yu, X Qin - Cellular & molecular immunology, 2010 - nature.com
The complement system, a key component of innate immunity, is a first-line defender against
foreign pathogens such as HIV-1. The role of the complement system in HIV-1 pathogenesis …

Complement receptors in HIV infection

S Doepper, L Kacani, B Falkensammer… - Current molecular …, 2002 - ingentaconnect.com
Similar to other pathogens, HIV can directly activate the complement pathway even in the
absence of antibodies. During and after seroconversion, HIV-specific antibodies enhance …

Complement–HIV interactions during all steps of viral pathogenesis

H Stoiber, Z Banki, D Wilflingseder, MP Dierich - Vaccine, 2008 - Elsevier
Upon crossing the endothelial barrier of the host, HIV initiates immediate responses of the
immunity system. Among its components, the complement system is one of the first the first …

Complement in different stages of HIV infection and pathogenesis

C Speth, H Stoiber, MP Dierich - International archives of allergy and …, 2003 - karger.com
The complement system is one of the most important weapons of innate immunity and is
involved in all infectious processes. It is not only a mechanism for direct protection against …

The supportive role of complement in HIV pathogenesis

H Stoiber, L Kacani, C Speth, R Würzner… - Immunological …, 2001 - Wiley Online Library
This review focuses on interactions of HIV with the first‐line defence of native immunity, the
complement system. In all body compartments tested so far, HIV meets complement …

Complement receptors in HIV infection

C Speth, L Kacani, MR Dierich - Immunological reviews, 1997 - Wiley Online Library
The complement system plays an important role in the antimicrobial defense of the
organism. Its components recognize a large variety of pathogens and target them for …

Complement and antibodies: a dangerous liaison in HIV infection?

H Stoiber, A Soederholm, D Wilflingseder… - Vaccine, 2008 - Elsevier
Due to ongoing recombination and mutations, HIV permanently escapes from neutralizing
antibody (nAb) responses of the host. By the masking of epitopes or shedding of gp120, HIV …

Emerging role for complement in HIV infection

G Huber, Z Banki, S Lengauer… - Current Opinion in HIV …, 2011 - journals.lww.com
Emerging role for complement in HIV infection : Current Opinion in HIV and AIDS Emerging
role for complement in HIV infection : Current Opinion in HIV and AIDS Log in or Register …

Role of complement in the control of HIV dynamics and pathogenesis

H Stoiber, C Speth, MP Dierich - Vaccine, 2003 - Elsevier
In all ex vivo preparations of HIV tested so far, C3 fragments and, after seroconversion,
antibodies were detected on the viral surface. This indicates that HIV survives complement …

HIV and human complement: inefficient virolysis and effective adherence

Z Bánki, H Stoiber, MP Dierich - Immunology letters, 2005 - Elsevier
Both, HIV envelope proteins gp120 and gp41 can directly activate complement system, even
in the absence of HIV-specific antibodies. During the budding process HIV acquires host …