In this study, we investigated locomotor activity and responses to repeated light and dark
stimuli to assess cannabinoid-induced abnormal behavior in zebrafish larvae (Danio rerio) …

Rationale The endocannabinoid system (ECS) comprises the cannabinoids anandamide
and 2-arachidonoylglycerol and the cannabinoid receptors 1 and 2 (Cnr1 and Cnr2). The …

Cannabidiol (CBD) has gained much attention in the past several years for its therapeutic
potential in the treatment of drug-resistant epilepsy, such as Dravet syndrome. Although …

Background: Valproic acid (VPA), an anticonvulsant used in epilepsy, has deleterious effects
on embryonic development and is considered an environmental risk factor for autism …

Cannabinoids are natural or synthetic compounds related chemically to (−)-(6aR, 10aR)-6,
6, 9-trimethyl-3-pentyl-6a, 7, 8, 10a-tetrahydro-6H-benzo [c] chromen-1-ol (Δ9-THC), the …

The Cannabis sativa plant contains numerous phytocannabinoids and terpenes with known
or potential biological activity. For decades, plant breeders have been breeding the …

In this study, we aimed to investigate the effect of the two main active cannabinoids extracted
from cannabis: Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on two distinct …

For centuries, the cannabis plant has been used as a source of food, fiber, and medicine.
Recently, scientific interest in cannabis has increased considerably, as its bioactive …

In light of legislative changes and the widespread use of cannabis as a recreational and
medicinal drug, delayed effects of cannabis upon brief exposure during embryonic …

Background Whole-plant cannabis extracts are consumed by the public for medical and non-
medical (“recreational”) purposes but are poorly researched compared to pure …