Increased incidences of Candida infection have augmented morbidity and mortality in
human population, particularly among severely immunocompromised patients and those …

The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Fungal infections are a veritable public health problem worldwide. The increasing number of
patient populations at risk (eg transplanted individuals, cancer patients, and HIV-infected …

Candida species are the leading cause of invasive fungal infections worldwide and are
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …

Fungal infections and, in particular, those caused by species of the Candida genus, are
growing at an alarming rate and have high associated rates of mortality and morbidity …

Introduction: Targeting pathogenetic mechanisms, rather than essential processes,
represents a very attractive alternative for the development of new antibiotics. This may be …

The very nature of infectious diseases has undergone profound changes in the past few
decades. Fungi once considered as nonpathogenic or less virulent are now recognized as a …

Background and Purpose: The incidence of fungal infection as well as candidemia has
increased significantly, contributing to morbidity and mortality in the developed countries …

Fungal infections have shown an upsurge in recent decades, which is mainly because of the
increasing number of immunocompromised patients and the occurrence of invasive …