Emerging virulence, drug resistance and future anti-fungal drugs for Candida pathogens
V Srivastava, RK Singla… - Current topics in medicinal …, 2018 - ingentaconnect.com
Increased incidences of Candida infection have augmented morbidity and mortality in
human population, particularly among severely immunocompromised patients and those …
human population, particularly among severely immunocompromised patients and those …
Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents
GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …
immune system of the host fails. Candida albicans is the most important and prevalent …
Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents
C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …
opportunistic pathogens and cause infections when the host becomes debilitated or …
New and promising chemotherapeutics for emerging infections involving drug-resistant non-albicans Candida species
LN Silva, TP de Mello… - Current Topics in …, 2019 - ingentaconnect.com
Fungal infections are a veritable public health problem worldwide. The increasing number of
patient populations at risk (eg transplanted individuals, cancer patients, and HIV-infected …
patient populations at risk (eg transplanted individuals, cancer patients, and HIV-infected …
[HTML][HTML] Drug resistance and novel therapeutic approaches in invasive candidiasis
SE Murphy, T Bicanic - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Candida species are the leading cause of invasive fungal infections worldwide and are
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …
An overview on conventional and non-conventional therapeutic approaches for the treatment of candidiasis and underlying resistance mechanisms in clinical strains
SB Salazar, RS Simões, NA Pedro, MJ Pinheiro… - Journal of Fungi, 2020 - mdpi.com
Fungal infections and, in particular, those caused by species of the Candida genus, are
growing at an alarming rate and have high associated rates of mortality and morbidity …
growing at an alarming rate and have high associated rates of mortality and morbidity …
Candidiasis drug discovery and development: new approaches targeting virulence for discovering and identifying new drugs
CG Pierce, JL Lopez-Ribot - Expert opinion on drug discovery, 2013 - Taylor & Francis
Introduction: Targeting pathogenetic mechanisms, rather than essential processes,
represents a very attractive alternative for the development of new antibiotics. This may be …
represents a very attractive alternative for the development of new antibiotics. This may be …
Non‐albicans Candida Infection: An Emerging Threat
SC Deorukhkar, S Saini… - … perspectives on infectious …, 2014 - Wiley Online Library
The very nature of infectious diseases has undergone profound changes in the past few
decades. Fungi once considered as nonpathogenic or less virulent are now recognized as a …
decades. Fungi once considered as nonpathogenic or less virulent are now recognized as a …
[HTML][HTML] Epidemiology and antifungal susceptibility of Candida species in a tertiary care hospital, Kolkata, India
P Bhattacharjee - Current medical mycology, 2016 - ncbi.nlm.nih.gov
Background and Purpose: The incidence of fungal infection as well as candidemia has
increased significantly, contributing to morbidity and mortality in the developed countries …
increased significantly, contributing to morbidity and mortality in the developed countries …
Antimycotic drugs and their mechanisms of resistance to Candida species
S Dahiya, N Sharma, A Punia, P Choudhary… - Current Drug …, 2022 - ingentaconnect.com
Fungal infections have shown an upsurge in recent decades, which is mainly because of the
increasing number of immunocompromised patients and the occurrence of invasive …
increasing number of immunocompromised patients and the occurrence of invasive …