Forward and reverse genetic dissection of morphogenesis identifies filament-competent Candida auris strains
DJ Santana, TR O'Meara - Nature communications, 2021 - nature.com
Candida auris is an emerging healthcare-associated pathogen of global concern. Recent
reports have identified C. auris isolates that grow in cellular aggregates or filaments, often …
reports have identified C. auris isolates that grow in cellular aggregates or filaments, often …
Rapid evolution of an adaptive multicellular morphology of Candida auris during systemic infection
Candida auris has become a serious threat to public health. The mechanisms of how this
fungal pathogen adapts to the mammalian host are poorly understood. Here we report the …
fungal pathogen adapts to the mammalian host are poorly understood. Here we report the …
Filamentation in Candida auris, an emerging fungal pathogen of humans: passage through the mammalian body induces a heritable phenotypic switch
H Yue, J Bing, Q Zheng, Y Zhang, T Hu… - Emerging microbes & …, 2018 - Taylor & Francis
Morphological plasticity has historically been an indicator of increased virulence among
fungal pathogens, allowing rapid adaptation to changing environments. Candida auris has …
fungal pathogens, allowing rapid adaptation to changing environments. Candida auris has …
Transcriptome Signatures Predict Phenotypic Variations of Candida auris
S Jenull, M Tscherner, N Kashko… - Frontiers in cellular …, 2021 - frontiersin.org
Health care facilities are facing serious threats by the recently emerging human fungal
pathogen Candida auris owing to its pronounced antifungal multidrug resistance and poor …
pathogen Candida auris owing to its pronounced antifungal multidrug resistance and poor …
Candida auris undergoes adhesin-dependent and -independent cellular aggregation
Candida auris is a fungal pathogen of humans responsible for nosocomial infections with
high mortality rates. High levels of resistance to antifungal drugs and environmental …
high mortality rates. High levels of resistance to antifungal drugs and environmental …
[HTML][HTML] In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris
Objective Candida auris has emerged as a health-care-associated and multidrug-resistant
fungal pathogen of great clinical concern. As many as 50% of C. auris clinical isolates are …
fungal pathogen of great clinical concern. As many as 50% of C. auris clinical isolates are …
[HTML][HTML] What do we know about the biology of the emerging fungal pathogen of humans Candida auris?
GB Ruiz, A Lorenz - Microbiological Research, 2021 - Elsevier
Candida auris is a worrisome fungal pathogen of humans which emerged merely about a
decade ago. Ever since then the scientific community worked hard to understand clinically …
decade ago. Ever since then the scientific community worked hard to understand clinically …
The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen
DJ Santana, G Zhao, TR O'Meara - Plos Pathogens, 2024 - journals.plos.org
Candida auris is an emerging fungal pathogen with unusual evolutionary history—there are
multiple distinct phylogeographic clades showing a near simultaneous transition from a …
multiple distinct phylogeographic clades showing a near simultaneous transition from a …
Ex Vivo Human and Porcine Skin Effectively Model Candida auris Colonization, Differentiating Robust and Poor Fungal Colonizers
EF Eix, CJ Johnson, KM Wartman… - The Journal of …, 2022 - academic.oup.com
Candida auris proliferates and persists on the skin of patients, often leading to health care-
associated infections with high mortality. Here, we describe 2 clinically relevant skin models …
associated infections with high mortality. Here, we describe 2 clinically relevant skin models …
Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes
V Lara-Aguilar, C Rueda, I García-Barbazán, S Varona… - Virulence, 2021 - Taylor & Francis
Candida auris has emerged as a fungal pathogen that causes nosocomial outbreaks
worldwide. Diseases caused by this fungus are of concern, due to its reduced susceptibility …
worldwide. Diseases caused by this fungus are of concern, due to its reduced susceptibility …