Cognitive impairment is a common feature of schizophrenia; however, its origin remains
controversial. Neurodevelopmental abnormalities clearly play a role in pre-morbid cognitive …

Cognitive impairment is a well-recognized key feature of schizophrenia. Here we review the
evidence on (1) the onset and sensitive periods of change in cognitive impairment before …

Cognitive impairment is a core feature of schizophrenia that is present across the course of
the illness. However, due to complexities of studying cognitive decline in patients prior to the …

Objective Despite the widespread belief that neuropsychological decline is a cardinal
feature of the progression from the premorbid stage to the chronic form of schizophrenia, few …

Schizophrenia patients commonly exhibit substantial and diffuse cognitive impairment.
Evidence suggests that subtle cognitive deficits are already apparent in childhood and …

Introduction: A wealth of evidence indicates that neurocognitive deficits are evident in
patients with schizophrenia at both illness onset and after many years of treatment. Little is …

BACKGROUND: Neurocognitive deficits are considered to be central to the pathophysiology
of schizophrenia, and the neurodevelopmental model suggests that such deficits precede …

Neurodevelopmental and neurodegenerative theories may be viewed as incompatible
accounts that compete to explain the pathogenesis of schizophrenia. However, it is possible …

Although a vast literature pertaining to neuropsychological deficits in schizophrenia has
amassed over the past 45 years, the exact timing and course of the neuropsychological …

Cognitive impairment is a core feature of schizophrenia. However, the longitudinal course
and pattern of this impairment, and its relationship to functional outcome, are not fully …