Specific expression and functions of circular RNAs

S Misir, N Wu, BB Yang - Cell Death & Differentiation, 2022 - nature.com
In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by
their covalently closed circular structure, have become a new research paradigm in RNA …

Circular RNA and its mechanisms in disease: from the bench to the clinic

B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …

[HTML][HTML] CircRNAs: role in human diseases and potential use as biomarkers

L Verduci, E Tarcitano, S Strano, Y Yarden… - Cell death & …, 2021 - nature.com
Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …

[HTML][HTML] Recent research progress on circular RNAs: Biogenesis, properties, functions, and therapeutic potential

AR Sharma, M Bhattacharya, S Bhakta, A Saha… - … Therapy-Nucleic Acids, 2021 - cell.com
Circular RNAs (circRNAs), an emerging family member of RNAs, have gained importance in
research due to their new functional roles in cellular physiology and disease progression …

[HTML][HTML] Circular RNA: an important player with multiple facets to regulate its parental gene expression

T Shao, Y Pan, X Xiong - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Circular RNAs (circRNAs), a novel type of endogenous RNAs with covalently closed-loop
structures, have become a new research hotspot in the RNA world. Their diversity, stability …

The emerging landscape of circular RNA in life processes

S Qu, Y Zhong, R Shang, X Zhang, W Song, J Kjems… - RNA biology, 2017 - Taylor & Francis
abstract Circular RNAs (circRNAs) are a novel class of non-coding RNA that assumes a
covalently closed continuous conformation. CircRNAs were previously thought to be the …

[HTML][HTML] The emerging roles and functions of circular RNAs and their generation

CY Yu, HC Kuo - Journal of biomedical science, 2019 - Springer
Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5'and 3'termini
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …

Circular RNAs in physiology and non-immunological diseases

L Chen, C Huang, G Shan - Trends in biochemical sciences, 2022 - cell.com
Circular RNAs (circRNAs) are covalently closed single-stranded RNAs. Four subclasses of
circRNAs have been identified in animal cells, and they have unique features in their …

[HTML][HTML] Deep insights in circular RNAs: from biogenesis to therapeutics

PT Mumtaz, Q Taban, MA Dar, S Mir, Z Haq… - Biological procedures …, 2020 - Springer
Circular RNAs (circRNAs) have emerged as a universal novel class of eukaryotic non-
coding RNA (ncRNA) molecules and are becoming a new research hotspot in RNA biology …

Circular RNA: a new star of noncoding RNAs

S Qu, X Yang, X Li, J Wang, Y Gao, R Shang, W Sun… - Cancer letters, 2015 - Elsevier
Circular RNAs (circRNAs) are a novel type of RNA that, unlike linear RNAs, form a
covalently closed continuous loop and are highly represented in the eukaryotic …