[HTML][HTML] Interplay between aging and other factors of the pathogenesis of age-related macular degeneration

J Blasiak, P Sobczuk, E Pawlowska… - Ageing Research …, 2022 - Elsevier
Highlights•Aging is the major risk factor for AMD.•The macula contains more than 60 kinds of
cells that may age at different rates.•The retinal aging in AMD is determined by its interplay …

Age-related macular degeneration (AMD): Alzheimer's disease in the eye?

K Kaarniranta, A Salminen… - Journal of …, 2011 - content.iospress.com
Age-related macular degeneration (AMD) is a late-onset, neurodegenerative retinal disease
that shares several clinical and pathological features with Alzheimer's disease (AD) …

Age-related macular degeneration: A two-level model hypothesis

MP Rozing, JA Durhuus, MK Nielsen, Y Subhi… - Progress in retinal and …, 2020 - Elsevier
Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …

Aging is not a disease: distinguishing age-related macular degeneration from aging

D Ardeljan, CC Chan - Progress in retinal and eye research, 2013 - Elsevier
Age-related macular degeneration (AMD) is a disease of the outer retina, characterized most
significantly by atrophy of photoreceptors and retinal pigment epithelium accompanied with …

[HTML][HTML] Age-related macular degeneration: epidemiology, pathophysiology, diagnosis, and treatment

H Vyawahare, P Shinde - Cureus, 2022 - ncbi.nlm.nih.gov
The greatest global root of irremediable amaurosis in the venerable is age-related macular
degeneration (AMD), a complex eye condition. Clinically, AMD is characterized as being in …

Cellular senescence in age‐related macular degeneration: can autophagy and dna damage response play a role?

J Blasiak, M Piechota, E Pawlowska… - Oxidative Medicine …, 2017 - Wiley Online Library
Age‐related macular degeneration (AMD) is the main reason of blindness in developed
countries. Aging is the main AMD risk factor. Oxidative stress, inflammation and some …

Current concepts in the pathogenesis of age-related macular degeneration

MA Zarbin - Archives of ophthalmology, 2004 - jamanetwork.com
Objective To review and synthesize information concerning the pathogenesis ofage-related
macular degeneration (AMD). Methods Review of the English-language literature. Results …

Mechanism of inflammation in age‐related macular degeneration

F Parmeggiani, MR Romano… - Mediators of …, 2012 - Wiley Online Library
Age‐related macular degeneration (AMD) is a multifactorial disease that represents the most
common cause of irreversible visual impairment among people over the age of 50 in …

Does senescence play a role in age-related macular degeneration?

G Malek, J Campisi, K Kitazawa, C Webster… - Experimental eye …, 2022 - Elsevier
Advanced age is the most established risk factor for developing age-related macular
degeneration (AMD), one of the leading causes of visual impairment in the elderly, in …

Mechanisms of age‐related macular degeneration and therapeutic opportunities

M van Lookeren Campagne, J LeCouter… - The Journal of …, 2014 - Wiley Online Library
As the age of the population increases in many nations, age‐related degenerative diseases
pose significant socioeconomic challenges. One of the key degenerative diseases that …