Integrative bioinformatics analysis of WDHD1: a potential biomarker for pan-cancer prognosis, diagnosis, and immunotherapy

Z Cui, F Zou, R Wang, L Wang, F Cheng… - World Journal of …, 2023 - Springer
Background Although WD repeat and high-mobility group box DNA binding protein 1
(WDHD1) played an essential role in DNA replication, chromosome stability, and DNA …

WD Repeat and HMG Box DNA Binding Protein 1: An oncoprotein at the hub of tumorigenesis and a novel therapeutic target

Z Zhang, Q Zhu - International Journal of Molecular Sciences, 2023 - mdpi.com
WD repeat and HMG-box DNA binding protein 1 (WDHD1) is a highly conserved gene from
yeast to humans. It actively participates in DNA replication, playing a crucial role in DNA …

[HTML][HTML] Prognosis prediction ability and prospective biological mechanisms of WDHD1 in hepatocellular carcinoma tissues

RQ He, JD Li, WY He, G Chen, ZG Huang, MF Li… - Electronic Journal of …, 2022 - Elsevier
Background Hepatocellular carcinoma (HCC) is a malignant tumor with complex
pathogenesis. In HCC, the possible roles of transcriptional factor WD repeat and HMG-box …

Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis

N Sato, J Koinuma, M Fujita, M Hosokawa, T Ito… - Clinical Cancer …, 2010 - AACR
Purpose: We attempted to identify novel biomarkers and therapeutic targets for lung and
esophageal cancers. Experimental Design: We screened for genes that were overexpressed …

WDHD1 is over‐expressed in nasopharyngeal carcinoma and may control the expression of ITGAV

JY Wu, YT Niu, SN Huang, YM Tan, ZD Yang… - FEBS Open …, 2023 - Wiley Online Library
Nasopharyngeal carcinoma (NPC) is a highly metastatic and invasive malignant tumor that
originates in the nasopharynx. The DNA‐binding protein WD repeat and HMG‐box DNA …

[HTML][HTML] The clinical significance of transcription factor WD repeat and HMG-box DNA binding protein 1 in laryngeal squamous cell carcinoma and its potential …

JY Wu, XL Lan, DM Yan, YY Fang, YX Peng… - … -Research and Practice, 2022 - Elsevier
Background Currently, high expression of WD repeat and HMG-box DNA binding protein 1
(WDHD1) has been found in a variety of tumors; but there is no research has been …

[Retracted] EF‐Hand Domain‐Containing Protein D2 (EFHD2) Correlates with Immune Infiltration and Predicts the Prognosis of Patients: A Pan‐Cancer Analysis

Y Wang, M Song, B Gao - Computational and Mathematical …, 2022 - Wiley Online Library
Background. EF‐hand domain‐containing protein D2 (EFHD2) has recently been reported
to participate in initiation of cancer. More evidence indicates that EFHD2 plays an important …

The involvement of WDHD1 in the occurrence of esophageal cancer as a downstream target of PI3K/AKT pathway

Q Xian, D Zhu - Journal of Oncology, 2022 - Wiley Online Library
Esophageal cancer is one of the most common malignant tumors in the world, which is
characterized by high incidence, strong invasiveness, high mortality, and poor prognosis. At …

[HTML][HTML] Pan-cancer analysis identifies YTHDF2 as an immunotherapeutic and prognostic biomarker

W Liu, C Liu, J You, Z Chen, C Qian, W Lin… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: N6-methyladenosine (m6A) modification is a dynamic and reversible post-
transcriptional RNA modification prevalent in eukaryotic cells. YT521-B homology domain …

An integrated omics study on the role of HDAC9 gene in the oncogenic events of human gastrointestinal-tract associated cancers

R Patra, J Chakraborty, NC Das, S Mukherjee - Human Gene, 2023 - Elsevier
Esophageal, pancreatic, and colorectal cancers are considered as the main cancers
associated with the gastrointestinal-tract taking a huge toll on human health. Exploring new …