[PDF][PDF] " PATHOGENESIS OF OVARIAN CANCER

SI LABIDI-GALY - access.archive-ouverte.unige.ch
Epithelial ovarian cancer (EOC) is a heterogeneous disease with five histotypes: serous
(highgrade and low-grade), endometrioid, clear cell and mucinous carcinomas. New …

[HTML][HTML] Morphological and molecular heterogeneity of epithelial ovarian cancer: Therapeutic implications

I Romero, S Leskelä, BP Mies, AP Velasco… - European Journal of …, 2020 - Elsevier
Ovarian epithelial cancer (OEC) is the most lethal gynecologic malignancy. Despite current
chemotherapeutic and surgical options, this high lethality can be attributed to multiple …

Paradigm shift in ovarian tumor pathology from the view of genomic abnormalities

Y Mikami - Gan to Kagaku ryoho. Cancer & Chemotherapy, 2016 - europepmc.org
A decade of accumulated evidence has led to significant progress and a paradigm shift in
ovarian tumor pathology. Now, ovarian carcinoma is widely recognized as a heterogeneous …

Pathogenesis, Genetics, and Genomics of Non–High Grade Serous Ovarian Cancers

N Ilenkovan, C Gourley - Hematology/Oncology Clinics, 2018 - hemonc.theclinics.com
Epithelial ovarian cancer consists of several separate diseases each with its own molecular
and histopathologic profile. High grade serous ovarian cancer is the commonest and …

[HTML][HTML] High grade serous ovarian carcinomas originate in the fallopian tube

SI Labidi-Galy, E Papp, D Hallberg, N Niknafs… - Nature …, 2017 - nature.com
High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of ovarian cancer
and has a poor outcome. It has been proposed that fallopian tube cancers may be …

[HTML][HTML] Coming into focus: the nonovarian origins of ovarian cancer

L Dubeau, R Drapkin - Annals of oncology, 2013 - Elsevier
Background The traditional view of epithelial ovarian cancer asserts that all tumor subtypes
share a common origin in the ovarian surface epithelium (OSE) Design A literature review …

Ovarian epithelial carcinogenesis

J Zhang, EG Silva, AK Sood, J Liu - Gynecologic and Obstetric Pathology …, 2019 - Springer
The mortality rate of epithelial ovarian carcinoma (EOC) ranks the highest in all
gynecological malignancies, although it is the third common cancer in the female …

Transcriptomic characterization of endometrioid, clear cell, and high-grade serous epithelial ovarian carcinoma

BL Fridley, J Dai, R Raghavan, Q Li, SJ Winham… - … , biomarkers & prevention, 2018 - AACR
Background: Endometrioid carcinoma (EC) and clear cell carcinoma (CC) histotypes of
epithelial ovarian cancer are understudied compared with the more common high-grade …

Morphological and molecular basis of ovarian serous carcinoma

DG Rosen, Z Zhang, W Shan, J Liu - Journal of biomedical research, 2010 - Elsevier
Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we
provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first …

Molecular Pathogenesis of Ovarian Cancer

PH Thaker, AK Sood - Gynecologic Cancers: A Multidisciplinary …, 2013 - books.google.com
Ovarian cancer remains the most lethal of all gynecologic malignancies due to the lack of
effective screening strategies, nonspecific symptoms at presentation, advanced stage at time …