Viromimetic STING agonist‐loaded hollow polymeric nanoparticles for safe and effective vaccination against Middle East respiratory syndrome coronavirus
The continued threat of emerging, highly lethal infectious pathogens such as Middle East
respiratory syndrome coronavirus (MERS‐CoV) calls for the development of novel vaccine …
respiratory syndrome coronavirus (MERS‐CoV) calls for the development of novel vaccine …
A novel nanobody targeting Middle East respiratory syndrome coronavirus (MERS-CoV) receptor-binding domain has potent cross-neutralizing activity and protective …
G Zhao, L He, S Sun, H Qiu, W Tai, J Chen, J Li… - Journal of …, 2018 - Am Soc Microbiol
ABSTRACT The newly emerged Middle East respiratory syndrome coronavirus (MERS-
CoV) continues to infect humans and camels, calling for efficient, cost-effective, and broad …
CoV) continues to infect humans and camels, calling for efficient, cost-effective, and broad …
Engineering a self-navigated MnARK nanovaccine for inducing potent protective immunity against novel coronavirus
Effective vaccines are vital to fight against the COVID-19 global pandemic. As a critical
component of a subunit vaccine, the adjuvant is responsible for strengthening the antigen …
component of a subunit vaccine, the adjuvant is responsible for strengthening the antigen …
Development of spike receptor-binding domain nanoparticles as a vaccine candidate against SARS-CoV-2 infection in ferrets
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a causative agent of the
CoV disease 2019 (COVID-19) pandemic, enters host cells via the interaction of its receptor …
CoV disease 2019 (COVID-19) pandemic, enters host cells via the interaction of its receptor …
Self-assembling nanoparticle vaccines displaying the receptor binding domain of SARS-CoV-2 elicit robust protective immune responses in rhesus monkeys
H Li, L Guo, H Zheng, J Li, X Zhao, J Li… - Bioconjugate …, 2021 - ACS Publications
SARS-CoV-2 caused the COVID-19 pandemic that lasted for more than a year. Globally,
there is an urgent need to use safe and effective vaccines for immunization to achieve …
there is an urgent need to use safe and effective vaccines for immunization to achieve …
Rapid development of SARS-CoV-2 spike protein receptor-binding domain self-assembled nanoparticle vaccine candidates
The coronavirus disease pandemic of 2019 (COVID-19) caused by the novel SARS-CoV-2
coronavirus resulted in economic losses and threatened human health worldwide. The …
coronavirus resulted in economic losses and threatened human health worldwide. The …
Heterologous prime–boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory …
SY Jung, KW Kang, EY Lee, DW Seo, HL Kim, H Kim… - Vaccine, 2018 - Elsevier
Abstract The Middle East respiratory syndrome coronavirus (MERS-CoV) is a highly
pathogenic and zoonotic virus with a fatality rate in humans of over 35%. Although several …
pathogenic and zoonotic virus with a fatality rate in humans of over 35%. Although several …
[HTML][HTML] Nanoparticle vaccines based on the receptor binding domain (RBD) and heptad repeat (HR) of SARS-CoV-2 elicit robust protective immune responses
Various vaccine strategies have been proposed in response to the global COVID-19
pandemic, each with unique strategies for eliciting immune responses. Here, we developed …
pandemic, each with unique strategies for eliciting immune responses. Here, we developed …
Multivalent nanoparticle-based vaccines protect hamsters against SARS-CoV-2 after a single immunization
S Chiba, SJ Frey, PJ Halfmann, M Kuroda… - Communications …, 2021 - nature.com
The COVID-19 pandemic continues to wreak havoc as worldwide SARS-CoV-2 infection,
hospitalization, and death rates climb unabated. Effective vaccines remain the most …
hospitalization, and death rates climb unabated. Effective vaccines remain the most …
A Mosaic Nanoparticle Vaccine Elicits Potent Mucosal Immune Response with Significant Cross‐Protection Activity against Multiple SARS‐CoV‐2 Sublineages
X Zhang, S Wu, J Liu, R Chen, Y Zhang, Y Lin… - Advanced …, 2023 - Wiley Online Library
Because of the rapid mutation and high airborne transmission of SARS‐CoV‐2, a universal
vaccine preventing the infection in the upper respiratory tract is particularly urgent. Here, a …
vaccine preventing the infection in the upper respiratory tract is particularly urgent. Here, a …