Ischemic postconditioning (IPCD) significantly reduces infarct size in healthy animals and
protects the human heart. Because obesity is a major risk factor of cardiovascular diseases …

Ischemic preconditioning (IPC) is a powerful phenomenon that provides potent
cardioprotection in mammalian hearts; however, the role of endothelial nitric oxide (NO) …

Ischaemic post‐conditioning (PostC) is a clinically relevant cardioprotective modality that
has been confirmed in many species including human. It remains unknown if PostC can still …

Objective: We tested whether ischemic postconditioning (IPostC) is protective in remodeled
myocardium. Methods: Post-myocardial infarct (MI)-remodeled hearts after permanent …

Insulin resistance (IR) precedes the onset of Type 2 diabetes, but its impact on
preconditioning against myocardial ischemia-reperfusion injury is unexplored. We examined …

Background. Coronary atherosclerosis has profound effects on vascular and myocardial
biology, and it has been speculated that the atherosclerotic heart does not benefit from …

Ischemic postconditioning (IPC) represents one of the most effective cardioprotective
strategies against myocardial ischemia/reperfusion. Depression is commonly present in …

Post-conditioning by repetitive cycles of reperfusion/ischemia after prolonged ischemia
protects the heart from infarction. The objectives of this study were: Are kinases (PI3-kinase …

Ischemic postconditioning (IPO) reduces lethal reperfusion injury under normal conditions,
but its effectiveness in hypercholesterolemia (HC) is disputed. We measured the …

Genetically engineered mice provide an excellent tool to study the role of a particular gene
in biological systems and will be increasingly used as models to understand the signal …