Exosome camouflaged coordination-assembled Iridium (III) photosensitizers for apoptosis-autophagy-ferroptosis induced combination therapy against melanoma
T Feng, Z Tang, J Karges, J Shen, C Jin, Y Chen, Y Pan… - Biomaterials, 2023 - Elsevier
Melanoma represents the most fatal form of skin cancer due to its resistance mechanisms
and high capacity for the development of metastases. Among other medicinal techniques …
and high capacity for the development of metastases. Among other medicinal techniques …
A Biodegradable Iridium (III) Coordination Polymer for Enhanced Two‐Photon Photodynamic Therapy Using an Apoptosis–Ferroptosis Hybrid Pathway
The clinical application of photodynamic therapy is hindered by the high glutathione
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …
Ferroptosis-apoptosis combined anti-melanoma immunotherapy with a NIR-responsive upconverting mSiO2 photodynamic platform
D Li, J Ren, J Li, Y Zhang, Y Lou, J Zhu, P Liu… - Chemical Engineering …, 2021 - Elsevier
Photodynamic therapy (PDT) is an appealing treatment for oncologic skin diseases owing to
its high spatiotemporally selectivity and non-invasive features. However, its application in …
its high spatiotemporally selectivity and non-invasive features. However, its application in …
Highly Efficient Far‐Red/NIR‐Absorbing Neutral Ir (III) Complex Micelles for Potent Photodynamic/Photothermal Therapy
A critical issue in photodynamic therapy (PDT) is inadequate reactive oxygen species (ROS)
generation in tumors, causing inevitable survival of tumor cells that usually results in tumor …
generation in tumors, causing inevitable survival of tumor cells that usually results in tumor …
Folate-targeted iridium complexes amplify photodynamic therapy efficacy through ferroptosis
X He, L Wei, J Chen, S Ge… - Inorganic Chemistry …, 2023 - pubs.rsc.org
Interest in targeted cancer therapies with fewer side effects has increased in recent years.
Photodynamic therapy (PDT) involves the use of photosensitizers (PSs) and light to …
Photodynamic therapy (PDT) involves the use of photosensitizers (PSs) and light to …
Iridium (III) complex–derived polymeric micelles with low dark toxicity and strong NIR excitation for phototherapy and chemotherapy
J Zhao, X Zhang, L Fang, C Gao, C Xu, S Gou - Small, 2020 - Wiley Online Library
Iridium (III) complexes are potent candidates for photodynamic therapy. However, their
clinical usage is impeded by their poor water solubility, high dark toxicity, and negligible …
clinical usage is impeded by their poor water solubility, high dark toxicity, and negligible …
Rosmarinic acid‐crosslinked supramolecular nanoassembly with self‐regulated photodynamic and anti‐metastasis properties for synergistic photoimmunotherapy
Y Zhou, Y Zhang, C Jiang, Y Chen, F Tong, X Yang… - Small, 2023 - Wiley Online Library
A primary concern about photodynamic therapy (PDT) is its inability to regulate the
generation levels of reactive oxidative species (ROS) based on the complex …
generation levels of reactive oxidative species (ROS) based on the complex …
[HTML][HTML] A mitochondria-localized iridium (iii) photosensitizer for two-photon photodynamic immunotherapy against melanoma
Conventional photodynamic therapy mainly causes a therapeutic effect on the primary tumor
through the localized generation of reactive oxygen species, while metastatic tumors remain …
through the localized generation of reactive oxygen species, while metastatic tumors remain …
Redox-activated porphyrin-based liposome remote-loaded with indoleamine 2, 3-dioxygenase (IDO) inhibitor for synergistic photoimmunotherapy through induction of …
Immunotherapy through stimulating the host immune system has emerged as a powerful
therapeutic strategy for various malignant and metastatic tumors in the clinic. However …
therapeutic strategy for various malignant and metastatic tumors in the clinic. However …
Rational assembly of a biointerfaced core@ shell nanocomplex towards selective and highly efficient synergistic photothermal/photodynamic therapy
C Qin, J Fei, A Wang, Y Yang, J Li - Nanoscale, 2015 - pubs.rsc.org
To optimize synergistic cancer therapy, we rationally assemble an inorganic–organic
nanocomplex using a folate-modified lipid bilayer spread on photosensitizer-entrapped …
nanocomplex using a folate-modified lipid bilayer spread on photosensitizer-entrapped …